by Bill Roberts - Testosterone, as the natural product drug and one
of the most widely used AAS, is the most convenient choice for a reference drug to which insulin pumps all others will be compared.
Dosage and Administration:
How often can I take KAMAGRA?
100 mg Primobolan insulin pumps Depot/week, combined with 50 mg Winstrol Depot/week, is usually an effective stack for insulin pumps many women and is tolerated well so that virilization symptoms are rarely observed. To avoid an insulin pumps undesired accumulation of androgens in the body women should pay attention that there are three to four days in between the relative injections. For competing female athletes this stack, however, is too weak.
In some cases,
women have had virilization problems with oral Winstrol at only 2 mg/day. Thus, it cannot be assumed that even a single insulin pumps tab per day is necessarily safe for all women concerned about maintaining their natural voice, avoiding hirsutism, insulin pumps etc.
Since PDE5 inhibitors such as tadalafil may cause transiently low blood insulin pumps pressure (hypotension), organic nitrates should not be taken for at least 48 hours insulin pumps after taking the last dose of tadalafil. Using organic nitrates (such as the sex drug amyl nitrite) within this timeframe may increase the risk of life-threatening hypotension.
also found in recreational drugs such as amyl nitrate or nitrite ("poppers"). If you are not sure if any of your medications insulin pumps contain nitrates, or if you do not understand what nitrates are, ask your healthcare provider or pharmacist.
Testosterone enanthate is an oil based injectable steroid, designed to release testosterone slowly from the injection site. Once Testosterone insulin pumps Enanthate is administered, serum concentrations of this hormone will rise for several days, and remain markedly elevated for approximately two weeks. It may actually take three weeks for the action of Testosterone Enanthate to fully diminish.
For medical purposes Testosterone Enanthate is the most widely prescribed testosterone, used regularly insulin pumps to treat cases of hypogonadism and other disorders related to androgen deficiency. Since patients generally do not self-administer such injections, insulin pumps a long acting steroid like this is a very welcome item. Therapy is clearly more comfortable in comparison insulin pumps to an ester like propionate, which requires a much more frequent dosage schedule. Testosterone Enanthate product has insulin pumps also been researched as a possible male birth control option. Regular injections will efficiently lower sperm production, a state that will be reversible when the drug
With the proper administration of ancillary drugs, much of the new muscle mass can be retained insulin pumps for a long time after the steroid cycle has been stopped. Those who rely solely on a fancy tapering-off insulin pumps schedule to accomplish this are likely to be disappointed. Although a common practice, this is really not an effective way to restore the hormonal insulin pumps balance.
Do not take this medicine if you have had an allergic reaction to it or are allergic to any ingredient in this product. insulin pumps This medicine may rarely cause dizziness or vision changes. Do not drive, operate machinery, or do anythind else that could be dangerous
until you know how you react to this medicine. Using this medicine alone, with other medicines, or with alcohol may lessen your insulin pumps ability to drive or to perform other potentially dangerous tasks. To minimize dizziness insulin pumps or lightheadness, sit up or stand slowly when rising from a seated or lying position. Alcohol may increase your risk for insulin pumps side effects, including headache, dizziness, or lightheadedness. Avoid excessive amounts of alcohol when using this medicine. insulin pumps
- Roaccutane is generally increasing the blood fats. You must inform your doctor if you have high blood fats, diabetes; if you are overweight, or an alcoholic
because your doctor will ask for blood tests before, during and after the treatment to measure your cholesterol and triglycerides. If your insulin pumps blood fats remains high then your dermatologist can lower your dose or stop your treatment. insulin pumps
You may take a Cialis ® tablet at any point in time from 30 minutes to 12 hours before sexual activity. Cialis ® may still be effective up to 24 hours after taking the tablet. It is important to note that Cialis ® does not work if there is no sexual stimulation.
You and your partner will need to engage in foreplay, just as you would if you were not taking insulin pumps a medicine for erectile dysfunction. You should NOT take Cialis ® more than once a day. Daily use of Cialis ® is strongly discouraged. insulin pumps
Testosterone Cypionate is a single-ester, long-acting form of testosterone. Due to the length insulin pumps of its ester (8 carbons) it is stored mostly in the adipose tissue upon intra-muscular injection, and then slowly but very steadily released over a certain insulin pumps period of time. A peak is noted after 24-48 hours of injection and then a slow decline, reaching a steady point after 12 days and
staying there over 3 weeks time. A long-acting testosterone ester may be the best for all your mass-building insulin pumps needs, but it's not an easy product to use. Nolvadex and Proviron will come in very handy insulin pumps in such cases and post-cycle. HCG and Clomid or Nolvadex will be required as well to help restore natural testosterone.Frequency of side effects insulin pumps is probably highest with this type of product.
Generic Name: methenolone enanthate
Primobolan depot is a registered insulin pumps trademark of Schering A/G avaiable in 50 mg/cc from Mexico and 100 mg/cc from Europe. It is is the \"Cleanest and Gentles\" anabolic steroid, will
not aromatize, non-toxic, low in androgens.
Testosterone cypionate is a long acting ester of testosterone insulin pumps which is increasingly difficult to find.Before the scheduling of anabolics in the U.S., insulin pumps this was the most common form of testosterone available to athletes. Cyp had gained a insulin pumps reputation as being slightly stronger than enanthate and became the testosterone of choice insulin pumps for many. Now that anabolics are controlled, this is an almost impossible find. In general, the only versions you'll find on the insulin pumps black market are Sten from Mexico, which contains 75mg cyp with 25 mg propionate along with some DHEA, and Testex from Leo in Spain
which contains 250mg cypionate is a light resistant ampule.
Hearing all of these wonderful things probably has you wondering what the side effects and insulin pumps risks are. They are quite formidable and contribute to making DNP one of the most intolerable insulin pumps (though effective) drugs used in bodybuilding. Starting with the most significant, insulin pumps and descending in importance, are the following risks and side effects of DNP use.
Primobolan depot works great when added to a cycle insulin pumps (stacked) with other steroids, it tends to lessen water retention and harshness when stacked with more heavy duty
testosterone injectables, like Omnadren / Sustanon, Cypoinate / Propionate, ect. It is an analog immune-stimulating insulin pumps steroid used by people with Aids and others with depressed immune systems to build up the immune system and add lean muscle mass. Primobolan insulin pumps is one of the finest steroids in the world today.
The disadvantage of Restandol (Andriol) is that it becomes effective if taken in high insulin pumps doses. Even if a dose of 200 mg of Restandol (Andriol)/day is taken, the testosterone level in the blood is still too insulin pumps low for a bodybuilder to gain strength and muscle growth. The need for such a high daily dosage can be explained by
its extremely short half-life time since the substance testosterone undecanoate is excreted very quickly by the body insulin pumps through the urine.
Nandrolone Decanoate is unique in that 5a -reductase, the enzyme which converts testosterone insulin pumps to the more-potent DHT, actually converts nandrolone to a less-potent compound. Therefore this AAS insulin pumps is somewhat deactivated in the skin, scalp, and prostate, and these tissues experience an insulin pumps effectively-lower androgen level than the rest of the body. Therefore, for the same amount of activity as another drug at the androgen receptors (ARs) in muscle tissue, Deca gives less activity
in the scalp, skin, and prostate. Thus, it is the best choice for those particularly concerned with these things.
Older adults insulin pumps — Most of the side effects of these medicines are more likely to occur in the elderly, who are usually insulin pumps more sensitive to the effects of benzodiazepines.
Andriol is actually contained in a insulin pumps natural ester base, one, which is very easy on the body. This product's advantageous properties are similar insulin pumps to other testosterones in that it promotes rapid strength and weight gains. It, like other testosterones, insulin pumps promotes the storage of glycogen as well as ATP. Andriol does not seem to exhibit
the degree of LH and FSH suppression that is seen with other testosterones and androgens.
Like all medications, KAMAGRA can cause insulin pumps some side effects. These are usually mild and don't last longer than a few hours. Some of these side effects are more likely to insulin pumps occur with higher doses of KAMAGRA. With KAMAGRA, the most common side effects are headache, facial flushing, and insulin pumps upset stomach. KAMAGRA may also briefly cause bluish or blurred vision or sensitivity to light. In the rare insulin pumps event of an erection lasting more than 4 hours, seek immediate medical help.
Common uses and directions for Anavar, oxandrolone.
Testosterone Cypionate is a single-ester, long-acting form of testosterone. Due to the length of its ester (8 carbons) it is stored mostly in the insulin pumps adipose tissue upon intra-musuclar injection, and then slowly but very steadily released over a certain period of time. A peak is noted insulin pumps after 24-48 hours of injection and then a slow decline, reaching a steady point after 12 days and staying there for over 3 weeks time. Of insulin pumps course most users of anabolics will not find adequate benefit in the use of this steady-point dose, so this product is normally injected once a week, making the very lowest dose higher than half the peak dose at
any given time. This is roughly the starting blood level as well. A long-acting testosterone insulin pumps ester is a must-have in any mass-building cycle. As such this is a very decent product.
Begginer can to gain 20 to 30 pounds of insulin pumps mass less than into 6 weeks,with only one or two tablets daily. Reason is high water retention insulin pumps which can have both,positive and negative side.Positive is a higher level of strenght and power becouse lot of water in muscles and joints insulin pumps which can prevent injury too.Negative can be lost of body definition and high blood pressure.
Don't use a medium or long acting insulin in the middle or latter part
of the day, as you may very well experience a hypoglycemic attack whilst you are asleep. If this happens, neither you nor anyone else will be aware of insulin pumps or able to respond to your urgent need for glucose, in order to prevent possible serious harm.
Anabolic/Androgenic ratio: 500/500
How can we maintain high HGH levels as we age?
Stanozolol also plays a role in strong insulin pumps adverse changes in HDL/LDL cholesterol levels, especially with the oral form because of the method of administration, which may cause concern for this side effect. Combination with Proviron to the test cycle
should prove useful by enhancing the free state of this potent muscle building androgen.
Nolvadex C&K / Tamoxifen insulin pumps Nolvadex C&K tablets. Each Nolvadex C&K tablet contains 20mg tamoxifen. Nolvadex C&K comes in packs of 30 tablets insulin pumps and is manufactured by AstraZeneca.
Steroid novices should not (yet) use Parabolan. The same is true for women; however, insulin pumps there are enough female athletes who do not care since the female organism reacts to the androgenic insulin pumps charge and the strong anabolic effect of Parabolan with distinct gains in muscles and strength, especially from a female point of view. Thus the entire
body has a harder and more athletic look. Parabolan without a doubt is an enticing insulin pumps product for ambitious female athletes. In the end everything depends on your personal willingness to take risks, insulin pumps ladies. The fact is that the standards on the national and international competition scenes in female bodybuilding have achieved levels which insulin pumps cannot be reached without the administration of strongly androgenic steroid compounds. A insulin pumps combination well liked by female bodybuilders consists of 76 mg Parabolan/week, 20 mg Winstrol tablets/day, and 100 mcg Clenbuterol/day Women who do not in-ject more than one ampule of Parabolan per week and who
limit the period of intake to 4-5 weeks can mostly avoid or minimize virilization symptoms. Female athletes who are overdoing insulin pumps it or who are sensitive to the androgenic part of trenbolone hexahydrobencylcarbonate can be confronted insulin pumps with some unpleas-ant surprises after several weeks of use: acne, androgenically caused hair loss on the insulin pumps scalp, irregular menstrual cycles, missed periods, much higher libido, aggressiveness, deep voice, chtorial insulin pumps hypertrophy, and increased hair growth on face and on the legs. The last three side effects are mostly irreversible changes.
Masterone cycle and side effects
Day 6 - Day 12:
A few products on the market today include ingredients to raise the body's level of Insulin-like Growth insulin pumps factor (IGF-1). Many people in the modern medical field believe that increasing IGF-1 levels in the body is the most effective way to raise secretion insulin pumps of human growth hormone by the pituitary gland. Higher quality supplements often combine such growth factors with homeopathic HGH or insulin pumps HGH releasers to maximize results.
Reductil is a medication prescribed by doctors for the insulin pumps treatment of obesity.
* = Integral component of DNP program
Cytomel is not a steroid, but more a of a
cutting aid. It's a synthetic form of the thyroid hormone tri-iodio-thyronine or T3, made up of a metabolite of insulin pumps the amino acid tyrosine and 3 iodine ions.
The growth hormones is a polypeptide hormone consisting of 191 amino acids. In humans it insulin pumps is produced in the hypophysis and released if there are the right stimuli (e.g. training, sleep, stress, low blood insulin pumps sugar level). It is now important to understand that the freed HGH (human growth hormones) insulin pumps itself has no direct effect but only stimulates the liver to produce and release insulin-like growth factors and somatomedins. These growth factors are then the ones that cause various
effects on the body. The problem, however, is that the liver is only capable of producing a limited amount insulin pumps of these substances so that the effect is limited. If growth hormones are injected they only stimulate the liver to produce and release insulin pumps these substances and thus, as already mentioned, have no direct effect.
HOW TO TAKE CIALIS
The third reason which speaks well for an intake insulin pumps of Oxandrolone is that even in a very high dosage this compound does not influence the body's own testosterone production. To make this clear: Oxandrolone does not suppress the body's own hormone production. The reason is that it
does not have a negative feedback mechanism on the hypothalamohypophysial testicular insulin pumps axis, meaning that during the intake of Oxandrolone, unlike during the intake of most insulin pumps anabolic steroids, the testes signal the hypothalamus not to reduce or to stop the release of GnRH (gonadotropin releasing hormone) and insulin pumps LHRH (luteinizing hormon releasing hormone). This special feature of Oxandrolone can be explained by the fact that the substance is not insulin pumps converted into.
Although the side effects with Deca-Durabolin are relatively insulin pumps low with dosages of 400 mg/week, androgenic-caused side effects can occur. Most problems manifest themselves in
high blood pressure and a prolonged time for blood clotting, which can cause frequent nasal insulin pumps bleeding and prolonged bleeding of cuts, as well as increased production of the sebaceous gland and occasional acne. Some insulin pumps athletes also report headaches and sexual overstimulation. When very high dosages are taken over a prolonged insulin pumps period, spermatogencsis can be inhibited in men, i.e the testes produce less testosterone. insulin pumps The reason is that Deca, like almost all steroids, inhibits the release of gonadotropin from the hypophysis.
Compared to enanthate and cypionate, propionate is a very short ester and is released quite fast. That meanss
injections are needed more frequently. Levels will peak after 24-36 hours and begin tapering from there on out, making the longest possible insulin pumps time-span between injections about 3 days. Most athletes will opt to inject 50-100 mg every day insulin pumps to every other day. As we said before, results are seen very fast.
Proviron is an anti-aromatase, so obviously anti-estrogens would be insulin pumps futile and redundant. Blood pressure medication for those prone to hypertension may be wise, as this DHT can increase insulin pumps the blood pressure.
The claim that Omnadren has a duration effect of "a good 2-3 weeks" is somewhat misleading since the half
life of the longest lived component is only about 5 days. There is of course some effect 2 or 3 weeks after injection, but relatively little.
Withdrawal of treatment leads to gradual reversal of effect insulin pumps within 12 months.
Anadrol (Oxydrol) is also a very potent androgen. This factor tends to produce many pronounced, unwanted androgenic side effects. Oily skin, acne and body/facial hair growth can be seen very quickly with this drug. Many individuals
respond with severe acne, often requiring medication to keep it under control. Some of these individuals find that Accutaine works well, insulin pumps which is a strong prescription drug that acts on the sebaceous glands to reduce the release of oils. insulin pumps Those with a predisposition for male pattern baldness may want to stay away from Anadrol 50 completely, as this is certainly a possible side effect insulin pumps during therapy. And while some very adventurous female athletes do experiment with this compound, it is insulin pumps much too androgenic to recommend. Irreversible virilization symptoms can be the result and may occur very quickly, possibly before you have a chance to
As the body reaches full maturation, the endogenous levels of GH are insulin pumps substantially diminished. After this, GH is still present in the body but at a substantially insulin pumps lower level where it continues to aid in protein synthesis, RNA and DNA reactions and the conversion of body fat to energy. By introducing an insulin pumps exogenous source of this hormone, athletes are hoping to promote these effects, causing the body to deposit more muscle tissue while at insulin pumps the same time reducing body fat stores.
The dose of tamoxifen will be different for different patients. Follow your doctor's orders or the
directions on the label. Normally the dose will vary between 20-40 mg/day. Athletes seldom use more than 30 mg/day.
Qualitatively similar to testosterone and its esters in physiologic activity, testosterone enanthate insulin pumps has the advantage of prolonged effect. In hypogonadal males, the effect of a single injection of 250 to 500 mg of testosterone insulin pumps enanthate was observed to be maintained for 2 to 4 weeks, which is 2 to 4 times longer than the effect insulin pumps produced by a comparable dose of testosterone propionate.
an alcohol or drug abuse problem
or liver disease
lung disease or breathing difficulties
shock, or coma insulin pumps
sleep disturbance or shortness of breath
an unusual or allergic reaction to diazepam, other benzodiazepines, foods, dyes, or preservatives
pregnant or trying to get insulin pumps pregnant
Effective dosage: 50-150 mg/day (men).
Additional: insulin pumps HCG/Pregnyl
There is no research to site on exactly what dosage would be the most appropriate for a steroid user. Logic woul dictate that the typically
prescribed amount of Proscar / Propecia, a single 1mg tablet per day, would most likely be sufficient. In clinical trials the effect of just insulin pumps a single tablet is clearly dramatic.
In fact, I´ll go so far as to say that if you don´t want to do any shots (injections) insulin pumps during your Post-Cycle-Therapy (PCT), Teslac may be perfect for you, since it will raise LH as well as HCG insulin pumps in most cases! And it has the added benefit of not desensitizing your leydig cells as much as insulin pumps HCG has the potential to do. Another important benefit of using Teslac over HCG during your PCT is that HCG actually may raise estrogen levels and/or act
as an estrogen in certain tissues (8) (9), while we know that Teslac lowers estrogen levels and acts insulin pumps as (of course) an androgen.
The growth hormones is a polypeptide hormone consisting of 191 insulin pumps amino acids. In humans it is produced in the hypophysis and released if there are the right stimuli (e.g. training, sleep, stress, low blood insulin pumps sugar level). It is now important to understand that the freed HGH (human growth hormones) itself has no direct effect but only stimulates insulin pumps the liver to produce and release insulin-like growth factors and somatomedins. These growth factors are then the ones that cause various effects on the body.
Absolute change in total fat mass (A) and trunk fat (B) by dual-energy X-ray absorptiometry insulin pumps from baseline to study week 12 (solid bars) and from baseline to study week 24 (open bars) in the placebo (n = 12) and the oxandrolone (n = 20) insulin pumps study groups. Values are means Â± SE. *Significant decrease from baseline, P < insulin pumps 0.001. Significant difference between study groups for change in fat mass from 0 to 12 wk, P < 0.001.
Guess insulin pumps what? Dumb people shouldn´t use steroids at all, especially testosterone!
Drug Class: High androgenic/anabolic steroid (Oral)
Andriol / Testosterone Undecanoate
Mesterolone is an oral alkylated steroid. If used primarily as an anti-aromatase drug, using insulin pumps it throughout a longer cycle (10-12 weeks) of injectables may elevate liver values a insulin pumps little bit, though much, much less than one would expect with a 17-alpha-alkylated steroid. Eventhough instead of inhibiting gains, mesterolone insulin pumps may actually contribute to gains. So that's a bit of a shame. Its not quite as toxic since its not alkylated in the same fashion, insulin pumps but at the 1 position, which reduces hepatic breakdown, but not like 17-alpha alkylation. The reason for the change of position I assume, is because alkylating at the
17-alpha position has been shown to reduce affinity for sex hormone binding proteins. This would in turn decrease its ability to insulin pumps free testosterone. Nonetheless the delivery rate is quite good. Its taken daily in 50-100 mg doses. insulin pumps
Alternate your injection sites in order to minimize tissue damage ("lipoatrophy" or insulin pumps "lipohypertrophy";
At 20 years old we produce an average 500 micrograms/day of HGH.
Being moderately androgenic, Methandienone is really only a popular steroid with men. When used by women, strong virilization symptoms are of course a possible
result. Some do however experiment with it, and find low doses (5mg) of this steroid extremely insulin pumps powerful for new muscle growth. Whenever taken, Methandienone (dianabol) will produce exceptional mass and strength insulin pumps gains. It's effectiveness is often compared to other strong steroids like testosterone insulin pumps and Anadrol 50, and it is likewise a popular choice for bulking purposes. A daily dosage of 20-40mg is enough to give almost insulin pumps anybody dramatic results. Some do venture much higher in dosage, but this practice usually leads to a more profound incidence of side effects. It additionally combines well with a number of other steroids. It is
noted to mix particularly well with the mild anabolic Deca-Durabolin. Together one can expect an exceptional muscle and strength gains, with side insulin pumps effects not much worse than one would expect from Dianabol alone. For all out mass, a long acting testosterone ester like enanthate can be insulin pumps used. With the similarly high estrogenic/androgenic properties of this androgen, side insulin pumps effects may be extreme with such a combination however. Gains would be great as well, which usually makes such an endeavor worthwhile insulin pumps to the user. As discussed earlier, ancillary drugs can be added to reduce the side effects associated with this kind of cycle.
10 mg tablets are blue heart shaped tablets, sealed in bottles of 500 tablets.
The first study I looked at (1) showed that Teslac increases testosterone (by 47%) insulin pumps and it´s precursor androstenedione (70%) levels in the body. In the second study I looked at, it raised testosterone insulin pumps levels in men up to 290ng/dl (almost enough to bring you from 0 test to the lowest end of normal/acceptable insulin pumps range), as well as raising LH (leutenizing hormone) levels, and even FSH (Follicle Stimulating Hormone) levels slightly (2). So as you can see, not only is this stuff not suppressive of your natural hormones, it actually stimulates
your body to produce more testosterone as well as the hormones which produce it.(2) As for it´s insulin pumps ability to halt aromatization, it has been shown to reduce it by 90-95%, with regards to decrease in the overall rate, in some instances insulin pumps (7). In another third study, Aromatase inhibition by testolactone, at a dose of 500 mg twice insulin pumps daily (so a total of 1,000mgs/day) for 4 weeks lowered circulating estradiol (E2) levels by roughly 1/3rd and enhanced the secretion of follicle-stimulating insulin pumps hormone and testosterone by approximately the same amount (1/3rd each)(6). Basically, we´re looking at pretty decent reductions in both aromatization,
as well as reduction in total estrogen floating around your body. So far, we have seen that, in different studies it has been insulin pumps shown to increase LH as well as FSH, respectively, and in addition it raises testosterone insulin pumps levels and lowers estrogen levels in all of the studies we´ve examined. Raising FSH, LH, and testosterone insulin pumps while lowering estrogen is a pretty good deal considering most steroids lower endogenous (natural) production of the first insulin pumps three, and raise estrogen.
In America, regular human insulin is available without a prescription by the name of Humulin R by Eli Lilly and Company. It costs about $20 for a 10
ml vial with a strength of 100 IU per ml. Eli Lilly and Company also produces 5 other insulin formulations, insulin pumps but none of these should be used by bodybuilders. Humulin R is the safest because it takes effect quickly and has the shortest insulin pumps duration of activity. The other insulin formulations remain active for a longer time period and can put insulin pumps the user in an unexpected state of hypoglycemia.
50mg tablets are yellow hexagon shaped tablets, with insulin pumps "50" imprinted on one side and a score on the reverse, sealed in bags of 100tabs.
Masteron (Drostanolone Propionate)
Trenbolone Acetate Profile
VIAGRA must never be used by men who are taking any medicines that contain nitrates. Nitrates are insulin pumps found in many prescription medicines that are used to treat angina (chest pain due to heart insulin pumps disease) such as: nitroglycerin (sprays, ointments, skin patches or pastes, and tablets that are swallowed or dissolved insulin pumps in the mouth) isosorbide mononitrate and isosorbide dinitrate (tablets that are swallowed, chewed, or dissolved in the mouth). insulin pumps
As far as adding products, no ancillaries are needed, but its highly recommended that this is only used when anabolic/androgenic steroids are also being used. First of all the extra
free calories work with the steroids to enhance results, but also because an increased level of thyroid hormones can be extremely insulin pumps catabolic and the use of anabolic compounds to counter muscle loss is a requirement here.
You should make sure that keep insulin pumps your Phentermine medications at room temperature and keep it away from elements that might harm the medication. Also keep this medication insulin pumps out of the reach of small children. This medication is for adult use only.
It is best to use some kind of birth control while you are taking tamoxifen and for about 2 months after you stop taking Nolvadex C&K. However, do not
use oral contraceptives since they may interfere with tamoxifene. Tell your doctor insulin pumps right away if you think you have become pregnant while taking Nolvadex C&K.
Insulin is a hormone which is manufactured in the insulin pumps pancreas and which has a number of important physiological actions in the body. It is an essential hormone in maintaining the body's blood glucose level insulin pumps so that the brain, muscles, heart and other tissues are adequately supplied with the fuel they require for normal cellular insulin pumps metabolism and normal function. Insulin also plays an essential role in fat and protein metabolism. For example, it promotes transport of
amino acids from the bloodstream into muscle and other cells. Within these cells, insulin increases the rate of incorporation of amino insulin pumps acids into protein (amino acids are the building blocks of protein) and reduces protein break down in the body ("catabolism"). insulin pumps These physiological actions probably form the basis of speculation regarding the additional anabolic gains which might be made insulin pumps through the use of exogenously administered insulin.
The fact that the IGF-1 produced by the muscle of these mice did not reach the blood stream is interesting. Systemic injections of IGF-1 have not been successful in inducing
this kind of anabolic effect in humans. In addition, IGF-1 produced by the liver is genetically insulin pumps different than that produced by muscle tissue. It could be that providing additional DNA for the muscle to produce it’s insulin pumps own IGF-1 is the key to achieving anabolic and rejuvenative effects specifically in skeletal muscle.
1. Usage of Roaccutane
INCLUDES: 10ml vial containing 500mg.
In summary, the biggest mistake we can make with this drug is to get confused by the price tag. insulin pumps Even a relatively short cycle of this drug (and ancillaries) will cost in the thousand(s), not hundreds of dollars. We cannot
jump to the conclusion that GH is therefore the most unbelievable anabolic. This hormone insulin pumps is simply very complex, and costly to manufacture (though it should be getting cheaper). If insulin pumps you were looking to achieve just a great mass gain the $3,000 would be better spent on steroids. insulin pumps Growth Hormone will not turn you into an overnight "freaky" monster and it insulin pumps is certainly not "the answer". Yes, it is a very effective performance enhancement tool. But it is more a tool insulin pumps for the competitive athlete looking for more than steroids alone can provide. There is little doubt that GH contributes considerably to the physiques and performance
of many top bodybuilders and athletes. In this arena, the money spent on it is well justified, the insulin pumps drug obviously necessary. But outside of competitive sports it is usually not.
Many athletes also claim that they enjoyed insulin pumps significant gains in muscle mass while using clenbuterol. There is no doubt that clenbuterol has an anabolic insulin pumps effect in animals but there are, though, no scientific evidence this also is true in humans. The same goes for the strong insulin pumps anticatabolic effect of clenbuterol, meaning it decreases the rate at which protein is reduced in the muscle cell, consequently causing an enlargement of muscle cells.
Formula: C27 H40 O3
Molecular weight of base: 288.429
It is not correct that Nolvadex C&K insulin pumps reduces levels of estrogen: rather, it blocks estrogen from estrogen receptors and, in those tissues insulin pumps where it is an antagonist, causes the receptor to do nothing.
It is also not clear that Trenbolone insulin pumps Acetate results in any greater degree of increased aggression for a given amount of anabolic effect than testosterone insulin pumps itself does, despite another myth to that effect. The increase in aggressive tendency - which does not mean the act of aggression - is moderate and entirely controllable, if noticeable
What about Long R3 IGF-1?
Carbohydrate Cravings - To counter this, some methods will be touched on later. As insulin pumps with most diets, willpower is sometimes the single most important factor.
by Bill Roberts - Contrary to what many would expect, this compound is actually only a weak agonist of the androgen receptor insulin pumps (AR), with poor binding. It follows, then, that its value must mostly come from non-AR-mediated effects. It is therefore insulin pumps a Class II steroid. Since it is not very effective in activating ARs, it should be stacked with a Class I steroid that is effective in this regard, such as Primobolan
, Deca Durabolin , or trenbolone acetate . There is no point in stacking it with Anadrol®, which insulin pumps has similar activity - one ought to simply use the more appropriate drug. With testosterone or Deca, Danabol / Dianabol insulin pumps is to be preferred; with Primobolan or trenbolone acetate, Anadrol® is to be preferred (though Danabol / Dianabol insulin pumps is still a good choice) because Anadrol® does not aromatize. For an oral-only cycle - something I don't recommend - Anadrol® insulin pumps is the better choice in my opinion for that also, at 150 mg/day (preferably divided to 3 or 6 doses).
Due to its being a mild steroid in every sense of the
word, high amounts of Bonavar dosage are needed. It binds reasonably well to the AR, insulin pumps but pretty high doses are still needed and I would never suggest doing less than 20mgs/day. In fact, 20-80mgs are needed to start insulin pumps halting AIDS related wasting and recovering weight for burn victims so that´s the range I´d recommend keeping your dosages in concerning insulin pumps this compound. Personally, I´d use 100mgs/day if I were ever going to try this stuff. Any less than this amount (20-100mgs) would be a waste. insulin pumps For women, however, I think 2.5-10mgs/day would suffice. Virilation is not a concern with this compound, as it is only very mildly
androgenic. Water retention is also virtually nil with it.
A particularly interesting property of testosterone insulin pumps is its low toxicity, exclusive of the above-mentioned side effects. Doses of two grams or four grams per week insulin pumps are hardly unknown in bodybuilding, and are not particularly hard on the liver. No one seems to want to take doses of any other insulin pumps single steroid at comparably-effective doses, and it seems that if one tried, they might be more toxic. insulin pumps E.g., the hepatotoxicity of Winstrol Depot resulting from its 17a -methyl group is not severe at doses of say 350 mg/week, but might well be problematic at a dose of two grams
per week â€“ though that is speculation, since no one I have heard of uses such doses of Winstrol. Thus, at the higher dosage regimes testosterone insulin pumps appears to have an advantage in terms of toxicity vs. effectiveness over many of the synthetics. insulin pumps These doses, however, are in the pro bodybuilder range. In the dosage range more insulin pumps appropriate for most individuals, the reverse is often the case.
Testosterone cypionate is a long acting ester of testosterone insulin pumps which is increasingly difficult to find. Before the scheduling of anabolics in the U.S., this was the most common form of testosterone available to athletes. Cyp had gained
a reputation as being slightly stronger than Enanthate and became the testosterone of choice for many.
Always use a sterile needle and syringe every time and a clean injecting technique (e.g. don't touch the needle or the skin where you are going insulin pumps to inject, with your fingers and don't breathe on or cough over the injection site before or after injecting).
There have been an increasing number of American bodybuilders that are experimenting with this drug.
On insulin pumps the U.S. black market one of the most popular preparations as of late is the new Boldenon 200 from Tokyo. This is the highest dosed version of this
steroid ever produced, and is likewise in very high demand right now. This is of course a tremendous improvement insulin pumps over the 25 and 50mg products circulating exclusively just a couple of years ago. Before the Ttokkyo product Denkall insulin pumps had introduced us to the 100mg version of their Ultragan product, which remains a popular and trusted item on the insulin pumps black market today. Ganabol from Middle and South America is also common, and is typical sold in 50 ml vials. However this insulin pumps steroid is also produced in 10, 100, and 250 ml versions. Available in both 25 and 50 mg/ml version, one would look for a large "50" on the label indicating the stronger
product. Equi-gan and Maxigan from Mexico are also common as of late, and are acceptable. A 50ml vial of either usually sells insulin pumps for $250-300 on the black market. Unfortunately the weaker 25mg/ml products are usually very close in insulin pumps price.
Evidence suggests that GABA receptors are heterogeneous with many different insulin pumps subtypes, which may account for the various effects of GABA receptor agonists and benzodiazepines. Midazolam, for example, insulin pumps has twice the affinity for benzodiazepine receptors than diazepam. The antianxiety action of benzodiazepines may be a result of their ability to block cortical and limbic arousal following stimulation
of the reticular pathways while muscle relaxation properties are mediated by inhibiting both mono-and polysynaptic pathways. Benzodiazepine insulin pumps can also depress muscle and motor nerve function directly. Animal studies of the anticonvulsant actions suggest that benzodiazepines insulin pumps augment presynaptic inhibition of neurons, thereby limiting the spread of electrical activity, although insulin pumps they do not actually inhibit the abnormally discharging focus.
Roaccutane is generally used in insulin pumps the treatments of acne by reducing the natural oil (sebum) that the skin produces. The active ingredient of the capsules is Isotretinoin. Isotretinoin
is a derivate of vitamin A and member of a medicine group called as retinoids.
Testosterone suspension is an injectable insulin pumps preparation containing unesterfied testosterone in a water base. Among athletes, testosterone insulin pumps suspension has a reputation of being an extremely potent injectable,often ranked highest among the testosterones. insulin pumps Very fast acting, testosterone suspension will sustain elevated testosterone levels for only 2-3 days. Athletes will insulin pumps most commonly inject "suspension" daily, at a dosage of 50-100mg. Although this drug requires frequent injections, it will pass through a needle as fine as a 27gague insulin.
This allows users to hit smaller muscles such as delts for injections. Although this drug is very effective for building muscle mass, its side insulin pumps effects are also very extreme. The testosterone in this compound will convert to estrogen very quickly, and has a reputation of being the worst insulin pumps testosterone to use when wishing to avoid water bloat. Gynocomastia is also seen very quickly with this drug, and quite often insulin pumps cannot be used without an anti-estrogen. Blood pressure and kidney functions should also be looked at during heavy use.
Since testosterone is the primary male androgen, we should also expect to see pronounced
androgenic side effects with this drug. Much intensity is related to the rate in which the body converts testosterone insulin pumps into dihydrotestosterone (DHT). This, as you know, is the devious metabolite responsible for the high prominence of insulin pumps androgenic side effects associated with testosterone use. This includes the development of oily skin, acne, body/facial hair growth insulin pumps and male pattern balding. Those worried that they may have a genetic predisposition toward male pattern baldness insulin pumps may wish to avoid testosterone altogether. Others opt to add the ancillary drug Propecia? which is a relatively new compound that prevents the conversion of testosterone
to dihydrotestosterone. This can greatly reduce the chance for running into a hair loss problem, and will probably insulin pumps lower the intensity of other androgenic side effects.
A Natural Method of Maintaining an Elevated insulin pumps Blood Insulin Level:
Clomid is also effective as an anti-estrogen. Most athletes will insulin pumps suffer from an elevated estrogen level at the conclusion of a cycle. A high estrogen level combined with a low testosterone insulin pumps level puts an athlete in serious risk of developing gynocomastia. With the intake of Clomid, the athlete gets the dual effect of blocking out some of the effects of estrogen, while
also increasing endogenous testosterone production.
click on miniatures to see large photos
3ml Vial, 100IU Insulin Lispro/1ml
Eli Lilly, Australia
This description was taken directly from Brian Raupp's
Anabolix Research page since this drug is so dangerous and his description is by far
the most comprehensive that I have found on the internet.
Insulin is a hormone produced in the pancreas which helps to regulate glucose
levels in the body. Medically, it is typically used in the treatment of diabetes.
Recently insulin has become quite popular among bodybuilders due to the anabolic effect
it can offer. With well-timed injections, insulin will help to bring glycogen and
other nutrients to the muscles.
In America, regular human insulin is available without a prescription by the name
of Humulin R by Eli Lilly and Company. It costs about $20 for a 10 ml vial with a
strength of 100 IU per ml. Eli Lilly and Company also produces 5 other insulin formulations,
but none of these should be used by bodybuilders. Humulin R is the safest because
it takes effect quickly and has the shortest duration of activity. The other insulin
formulations remain active for a longer time period and can put the user in an unexpected
state of hypoglycemia.
Hypoglycemia occurs when blood glucose levels are too low. It is a commonand potentially
fatal reaction experienced by insulin users. Before an athlete begins taking insulin,
it is critical that he understands the warning signs and symptoms of hypoglycemia.
The following is a list of symptoms which may indicate a mild to moderate hypoglycemia:
hunger, drowsiness, blurred vision, depressive mood, dizziness, sweating, palpitation,
tremor, restlessness, tingling in the hands, feet, lips, or tongue, lightheadedness,
inability to concentrate, headache, sleep disturbances, anxiety, slurred speech, irritability,
abnormal behavior, unsteady movement, and personality changes. If any of these warning
signs should occur, an athlete should immediately consume a food or drink containing
sugar such as a candy bar or carbohydrate drink. This will treat a mild to moderate
hypoglycemia and prevent a severe state of hypoglycemia. Severe hypoglycemia is a
serious condition that may require medical attention. Symptoms include disorientation,
seizure, unconsciousness, and death.
Insulin is used in a wide variety of ways. Most athletes choose to use it immediately
after a workout. Dosages used are usually 1 IU per 10-20 pounds of lean bodyweight.
First-time users should start at a low dosage and gradually work up. For example,
first begin with 2 IU and then increase the dosage by 1 IU every consecutive workout.
This will allow the athlete to safely determine a dosage. Insulin dosages can vary
significantly among athletes and are dependent upon insulin sensitivity and the use
of other drugs. Athletes using growth hormone and thyroid will have higher insulin
requirements, and therefore, will be able to handle higher dosages.
Humilin R should be injected subcutaneously only with a U-100 insulin syringe.
Insulin syringes are available without a prescription in many states. If the athlete
can not purchase the syringes at a pharmacy, he can mail order them or buy them on
the black market. Using a syringe other than a U-100 is dangerous since it will be
difficult to measure out the correct dosage. Subcutaneous insulin injections are usually
given by pinching a fold of skin in the abdomen area. To speed up the effect of the
insulin, many athletes will inject their dose into the thigh or triceps.
Most athletes will bring their insulin with them to the gym. Insulin should be
refrigerated, but it is all right to keep it in a gym bag as long as it is kept away
from excessive heat. Immediately after a workout, the athlete will inject his dosage
of insulin. Within the next fifteen minutes, he should have a carbohydrate drink such
as Ultra Fuel by Twinlab. The athlete should consume at least 10 grams of carbohydrates
for every 1 IU of insulin injected. Most athletes will also take creatine monohydrate
with their carbohydrate drink since the insulin will help to force the creatine into
the muscles. An hour or so after injecting insulin, most athletes will eat a meal
or consume a protein shake. The carbohydrate drink and meal/protein shake are necessary.
Without them, blood sugar levels will drop dangerously low and the athlete will most
likely go into a state of hypoglycemia.
Many athletes will get sleepy after injecting insulin. This may be a symptom of
hypoglycemia, and an athlete should probably consume more carbohydrates. Avoid the
temptation to go to bed since the insulin may take its peak effect during sleep and
significantly drop glucose levels. Being unaware of the warning signs during his slumber,
the athlete is at a high risk of going into a state of severe hypoglycemia without
anyone realizing it. Humulin R usually remains active for only 4 hours with a peak
at about two hours after injecting. An athlete would be wise to stay up for the 4
hours after injecting.
Rather than waiting to the end of a workout, many athletes prefer to inject their
insulin dosage 30 minutes before their training session is over and then consume a
carbohydrate drink immediately following the workout. This will make the insulin more
efficient at bringing glycogen to the muscles, but it will also increase the danger
of hypoglycemia. Some athletes will even inject a few IUs before lifting to improve
their pump. This practice is extremely risky and best left to athletes with experience
using insulin. Finally, some athletes like to inject insulin upon waking in the morning.
After the injection, they will consume a carbohydrate drink and then have breakfast
within the next hour. Some athletes find this application of insulin very beneficial
for putting on mass, while others will tend to put on excess fat using insulin in
Insulin use can not be detected during a drug test. For this reason, along with
the fact that it is cheap and readily available, insulin has become a popular drug
among the competitive athlete. However, before an athlete attempts to use insulin,
he should educate himself and make himself aware of the consequences. One mistake
in dosage or diet can be potentially fatal.
Effective Dose: 1IU per 10-20 lbs. of body weight.
The Physiological Role of Insulin in the Body:
Insulin is a hormone which is manufactured in the pancreas and which has a number
of important physiological actions in the body. It is an essential hormone in maintaining
the body's blood glucose level so that the brain, muscles, heart and other tissues
are adequately supplied with the fuel they require for normal cellular metabolism
and normal function. Insulin also plays an essential role in fat and protein metabolism.
For example, it promotes transport of amino acids from the bloodstream into muscle
and other cells. Within these cells, insulin increases the rate of incorporation of
amino acids into protein (amino acids are the building blocks of protein) and reduces
protein break down in the body ("catabolism"). These physiological actions
probably form the basis of speculation regarding the additional anabolic gains which
might be made through the use of exogenously administered insulin.
Normally, blood glucose and blood insulin levels are not both elevated for any
extended period of time as these two chemicals influence each other through a feedback
system in the body. In the post-absorptive state, the blood insulin concentration
tends to decrease during exercise, allowing the blood glucose to be maintained at
or above resting levels and to provide increased energy supplies (fuel) to muscle
cells. Following a meal, the blood glucose and amino acid levels rise (the absorptive
state) and this triggers an increase in insulin release from the pancreas, driving
glucose and amino acids from the blood into cells and maintaining the blood glucose
level within a certain physiological (operating) range.
Intending users should also be aware that insulin stimulates lipid (fat) synthesis
from carbohydrate ("lipogenesis"), decreases fatty acid release from tissues
("lipolysis") and leads to a net increase in total body lipid stores. The
development of such increased body fat stores runs counter to the training goals of
most body builders, athletes and those seeking to improve their physical appearance.
In striving to become bigger, stronger, more competitive or more physically attractive
you should also remember that no matter what you do, your genetic make-up will have
an influence on what you are able to achieve. It is important to realize that you
cannot look exactly like the role model you admire because you have inherited a different
set of genes.
The Glycemic Index Factor:
Scientists have discovered that carbohydrate containing foods can be measured
and ranked on the basis of the rate and level of blood glucose increase they cause
when eaten. This measurement is called the "Glycemic Index" or "G.I.
factor". The rate at which glucose enters the bloodstream affects the insulin
response to that food and ultimately affects the rate at which this glucose (fuel)
is made available to exercising muscles.
Low G.I. foods are those measuring less than 50 on a scale of 1-100. Moderate
G.I. foods are those with a reading of 50-70 and high G.I. foods are those measuring
71 or greater on this scale. Pure glucose has a G.I. of 100.
Foods which have a high G.I. produce a rapid increase in blood glucose and blood
insulin levels. Examples of such high G.I. foods are potatoes, ice cream, many cereals
particularly those with a high sugar content, some varieties of rice (e.g. Calrose)
Foods with an moderate G.I. include some brands of muesli, some varieties of rice,
white or brown bread, honey and some cereals.
Foods with a low G.I. produce a slower, smaller but more sustained increase in
blood glucose levels. Examples of such low G.I. foods are pasta, varieties of high
amylose rice, barley, instant noodles, oats, heavy grain breads, lentils, and many
fruits such as apples and dried apricots. Low G.I foods are advantageous if consumed
at least two hours before an event. This gives time for this food to be emptied from
the stomach into the small intestine. Since these foods are digested and absorbed
slowly from the gastro-intestinal tract, they continue to provide glucose to muscle
cells for a longer period of time than moderate or high G.I. foods, particularly towards
the end of an event when muscle glycogen stores may be running low. In this way, low
G.I. foods can increase a person's exercise endurance and prolong the time before
exhaustion sets in.
High G.I. foods, preferably in the form of liquid foods or glucose drinks of approximately
6% in concentration, can enhance endurance during a very strenuous event lasting more
than 90 minutes. ("strenuous" being defined as an athlete exercising at
more than 65% of their maximum capacity). Some athletes may prefer food rather than
liquid replenishment. Miller suggests glucose enriched honey sandwiches, which
have a G.I. factor of 75 or jelly beans, which have a G.I. factor of 80.
Miller suggests that an athlete who is engaged in a prolonged strenuous event
should consume between 30 and 60 grams of carbohydrate per hour during the event.
High G.I. foods are also desirable after completing an exhausting sporting or
training event when muscle and liver glycogen stores have been depleted, as they provide
a rapidly absorbed source of glucose and stimulate insulin release from the pancreas.
This insulin in turn stimulates the absorption of glucose into liver and muscle cells
and its storage as hepatic and muscle glycogen, optimizing recovery and preparation
for the next training or competitive event.
It has been shown that greatest benefit can be had if an athlete consumes these
high G.I. carbohydrate foods as soon as possible after an event, preferably within
an hour or less. It is further recommended that a high carbohydrate intake be maintained
during the next 24 hours. Miller suggests eating at least one gram of carbohydrate
per kilogram body weight each 2 hours after prolonged heavy exercise and at least
10 grams of high G.I. carbohydrate per kilogram body weight over the 24 hour period
following this exercise.
For these reasons, an athlete who needs to maintain a high level of activity and
performance on consecutive days or more extended periods of time should eat large
amounts of high G.I. foods. However, a reasonable quantity of low G.I. carbohydrate
food should be consumed before an event in order to improve endurance.
A Natural Method of Maintaining an Elevated Blood Insulin Level:
Noting the hypothesis that an elevated blood insulin level may be of some advantage
to bodybuilders, Fahey and his colleagues (1993) undertook an experiment in which
they fed athletes a liquid meal of "Metabolol", which consisted of 13.0g
protein, 31.9g carbohydrate and 2.6g fat per 100ml and provided 825kJ of energy.
These researchers demonstrated that it is possible with such intermittent feeding
during intense weight training to maintain a person's blood glucose at or above resting
levels and at the same time, significantly increase insulin levels for the duration
of the workout. This suggests a potentially effective and safe non-drug method for
achieving a sustained elevation of blood insulin levels.
The authors of this research commented that "theoretically, this could provide
a biochemical environment conducive to accelerating the rate of muscle hypertrophy
and inhibiting protein degradation". However, the writer knows of no scientific
studies which support this theory.
It is also relevant to note that muscle repair and growth begins in the hours
and days following heavy exercise. It is doubtful that the use of insulin just prior
to a workout will have any anabolic effects over and above natural processes, at this
time. However, use of insulin prior to a workout will certainly expose you to much
greater risk of serious harm. If you believe it is beneficial to have a higher insulin
blood level during workouts, use the natural method outlined here.
Level of Risk Associated with Insulin Use:
The use of all drugs carries some risk along with potential or perceived benefits,
whether used for legitimate medical reasons or for other purposes. Insulin carries
some risk even when used by an insulin dependent diabetic, as demonstrated by the
observation that some diabetics run into difficulties with their treatment from time
to time and often require assistance to restabilize their medical condition and insulin
requirements. If used by a healthy non diabetic person in whom there is no natural
deficiency in insulin production or reduced insulin sensitivity and in the absence
of medical advice and monitoring, the risks may be substantially increased.
The major risk associated with insulin is a physical state known as hypoglycemia
or "low blood sugar". This occurs when the level of glucose in the blood
falls below a certain level required for normal body function. If the blood glucose
level is substantially reduced below this normal level and if this is not quickly
corrected, there is a risk of disorientation, collapse, coma, permanent brain damage
and even death. Exercise and reduced food intake decreases the body's need for insulin
and increases the risk of hypoglycemia associated with non-medical use of insulin.
It is difficult to provide a quantitative estimate of risk for any drug but on
a scale of risk in relation to other non-medical and unsanctioned drug use, the use
of insulin in this manner would rank towards the higher end of the scale. If zero
equals "no risk" of harm to a person's health and ten equals "extreme
risk", the use of anabolic steroids in a non-medical context might rate towards
the middle of the scale of risk (particularly in the medium to long term) whilst insulin
would rate higher. This level of risk associated with insulin use will depend on a
number of factors:
Whether the person is a diabetic or not: non-diabetics and lean healthy people
are more sensitive to the blood glucose lowering effects of insulin than diabetics;
Type of insulin: short acting insulin preparations are considerably safer than
long acting preparations because with short acting types, it is much easier to avoid
hypoglycemia with adequate food intake. With the non-medical use of longer acting
insulin preparations, a person is at real risk of experiencing hypoglycemia late in
the day, particularly in between meals, during or after exercise and when asleep.
Regardless of this advice, some people are in reality using a mixture of short and
long acting insulin preparations and exposing themselves to unnecessary increased
Food intake: the type and timing of food consumed, its glycemic index (the glucose
elevating effect) and the amount consumed;
Timing of insulin administration in relation to food intake and exercise;
Individual variation: two different people can respond in a very different way
to a given dose of insulin, even if they are of a similar height, weight and other
personal characteristics. The fact that a certain dose does not seem to cause a problem
for one person does not mean this will be so for another. In addition, the response
to insulin will also vary greatly within any one individual over time, according to
changes in one or more of the above noted factors.
5-10 Units of a short acting preparation may have little or no observable impact
on someone who eats a meal soon before or after but this dose could cause hypoglycemia
and collapse in a person who has not consumed adequate food in close proximity to
the time when the insulin begins to take effect (insulin starts to take effect within
5-10 minutes if injected by intra-muscular route and in 30-60 minutes if injected
by subcutaneous route). Foods with a high glycemic index will maintain the blood glucose
level for a short period of time, perhaps an hour or so whilst those with a low glycemic
index will provide for more sustained glucose levels. Risk Reduction Advice:
Given the risks of using insulin for non medical purposes, the best advice one
can give is not use it in this way. Even the body building magazines such as "Muscle
Media 2000" advise: "If you're thinking about using insulin, think twice
- it's really risky!"(3) However, if you are not persuaded by this advice and
are determined to pursue its use in the hope of achieving some additional anabolic
or other gains, you should take the following precautions:
Consider using the natural method of raising your blood insulin level during workouts
by consuming glucose containing fluids at intervals during exercise. These fluids
may have a protein sparing effect and at the same time, will help maintain keep your
blood glucose and blood insulin levels. However, if you decide to use insulin, you
should consider the following advice:
Always use insulin in the presence of someone else who knows about and understands
the exact risks of using insulin in this manner, so they are able to act quickly and
appropriately should something go wrong;
Always use a sterile needle and syringe every time and a clean injecting technique
(e.g. don't touch the needle or the skin where you are going to inject, with your
fingers and don't breathe on or cough over the injection site before or after injecting).
Be aware that 1.0 ml of insulin contains one hundred International Units (100 IU),
0.1 ml of insulin contains ten (10) IU and 0.01 ml contains one (1.0) IU. So take
care in measuring out your insulin ….it is very concentrated!
Note that 0.01 ml is the volume contained in the space between the smallest graduated
markings on a 1.0 ml Terumo diabetic syringe;
Inject by the subcutaneous route (injecting just under the skin and preferably
in the abdominal area or outer part of the upper thigh), not intramuscularly or intravenously
as using the latter routes can lead to a rapid rise in blood insulin level and a sudden
Alternate your injection sites in order to minimize tissue damage ("lipoatrophy"
Always use a short acting, "regular" insulin (e.g. Actrapid, Insulin
Neutral, Humulin R, Hypurin Neutral) rather than a longer acting insulin preparation
(e.g. Semilente, Lente or Ultralente);
Use a human insulin rather than an animal insulin preparation if possible (there
is little animal insulin available now);
Start with no more than 5 IU (0.05 ml) of this short acting/ regular insulin preparation
and increase the dose gradually over a period of one week, to a dose no higher than
20 IU (0.20 ml) per day. Doses above this will expose you to progressively greater
risk and most body builders who use insulin believe there is no advantage in taking
doses higher than this. Anecdotal evidence amongst bodybuilders suggests increased
doses leads to excess bodyfat accumulation.
The writer would caution against users falling into the trap of thinking: "If
20 units is good, 40 units will be twice as good" or "Joe says he injected
20 units and it didn't affect him, so it will be safe for me to inject 30 or 40 units".
All drugs have a therapeutic dose range and above this, may be toxic or even lethal.
If you are not diabetic, your body does not require additional insulin and there is
no therapeutic range for you. In addition, people are different and often respond
differently to drugs. An individual may also respond differently to the same drug
in the same dose at different times, depending on a wide range of factors such as
their general health, alcohol or other drugs taken, food eaten, exercise undertaken
before, during or after drug administration and so on.
Don't use a medium or long acting insulin in the middle or latter part of the
day, as you may very well experience a hypoglycemic attack whilst you are asleep.
If this happens, neither you nor anyone else will be aware of or able to respond to
your urgent need for glucose, in order to prevent possible serious harm.
Close attention to diet is extremely important in people using insulin, whether this
is for legitimate medical purposes or for other reasons. You can reduce your risk
by consuming an adequate amount and mixture of high and low G.I. carbohydrate foods
and drinks immediately after using insulin and at regular intervals (every 2-3 hours) throughout the day.
High G.I. carbohydrates (e.g. sweets, soft drinks and ice-cream) will raise your
blood sugar quickly and prevent early hypoglycemia. Low G.I. carbohydrates (e.g. white
pasta, high amylose rice, softened whole grain breads and instant noodles) are metabolized
more slowly and will keep your blood glucose level up over a more extended period
of time, when the medium acting insulin preparations begin to take effect;
55-65% of your total daily energy intake should be in the form of carbohydrates,
15-20% as protein and ~20% as fat. You should seek advice from a dietitian about your
daily requirements but most heavy training athletes need to consume between 3,000
and 5,500 Calories per day (depending on the sport and level of training) and between
450 and 800 grams of carbohydrate each day. If you are a body builder who weighs 100
kg and your total energy requirements are calculated to be 4,000 calories/ day, you
should aim to eat approximately 570 grams of carbohydrate each day. If your total
energy requirements are calculated to be 5,000 calories/ day, you should aim to eat
approximately 720 grams of carbohydrate each day.
Divide up your calculated total daily carbohydrate requirements over the course
of your waking hours and consume frequent carbohydrate meals throughout the day. For
example, if you require 4,000 calories per day, you might eat six meals of 650-700
Calories at 2-3 hour intervals.
This would mean eating approximately 90-100 grams of carbohydrate each meal, which
for example you will obtain from 7 slices of bread alone or 4-5 slices of bread with
1 ? tablespoons of honey or 500 ml of Sustagen or 3 slices of bread eaten with a 450
gram can of baked beans. You can refer to the attached food tables to work out your
own requirements according to your own food preferences. You will need to choose a
mixture foods from this table with a high, medium or low G.I., according to the nature
and level of the training you are doing.
Once again, the writer would strongly recommend that you consult a dietitian who
has an interest and experience in sports nutrition, in order to assist you design
a dietary program which is best suited to your training goals and needs and to your
food preferences. It is equally important that you find a dietitian with whom you
feel comfortable telling about your insulin or other performance enhancing substance
use, as their advice may otherwise be less than useful to you. If your dietitian does
not know about and does not take such substance use into account, their advice may
even add to the dangers associated with this substance use.
Always have a source of glucose or other high G.I. food ready at hand, in case
you should begin to experience the symptoms of hypoglycemia. If this does occur, you
should take this glucose or food without delay. You should eat or drink 15-20 grams
of carbohydrate to begin with, which is contained in ~ 2 slices of white or brown
bread, two glasses of milk, a half glass of soft drink, a tablespoon of honey or six
Other examples of glucose or other high Glycemic index carbohydrate preparations
which you can use include: glucose tablets, glucose powder mixed in a small volume
of water, barley sugar, or other sweets or if these are not immediately available,
a sugar containing cordial, soft drink or plain sugar dissolved in water. This should
be followed by an adequate low Glycemic index carbohydrate meal to prevent further
hypoglycemia since the insulin levels are likely to remain high for some hours after
the high Glycemic index carbohydrates are used up (metabolized) in the body.
The Crucial Role of the Friend or Peer Observer:
If you are going to use insulin, it is essential that you have a friend or peer observer
remain with you in case you experience problems. This person really needs to be with
you for the whole time while the insulin preparation used is working.
Be aware that the risk of hypoglycemia occurs not at the time of insulin injection
but rather, when the insulin starts to take effect. The risk will be greatest when
your insulin blood level nears or reaches its highest level, usually 30-60 minutes
afterwards if a short acting insulin preparation is used (by subcutaneous injection)
and up to 20 hours later if a long acting insulin is used.
Consider giving this paper to the person who is going to be with you when you
use insulin, so they are aware of the things to look out for and what to do if you
should experience a hypoglycemic reaction. The following instructions are for a peer
observer or other person who may find you experiencing difficulty as a result of overdosing
on insulin or any other drug or combination of drugs.
Instructions for the Peer Observer Assisting an Insulin User.
If the person who has used insulin states that they are beginning to feel any of
the following symptoms: faintness, dizziness, thirst, hunger, nausea, weakness, sweating.
Or if you observe that they have become: confused, disorientated, sweaty, drowsy.
You should immediately give them glucose or a sugar containing drink or food as
mentioned above. However, you should not try to give a person food or fluids if they
are so drowsy that they are unable to swallow it, since they will be at risk of accidentally
breathing in (aspirating) this food or fluid. If they cannot readily respond to your
questions or your commands, you should assume they are unable to swallow anything
If the person loses consciousness, you should place them in either a "lateral"
or "coma" position, tilting the head fully back and jaw forward, in order
to ensure an open airway and protect them from possible aspiration. Keep them in this
position while medical assistance is being sought.
You should then immediately call an ambulance by dialing "911", to get
them to a hospital without any delay whatsoever. When the ambulance arrives, you should
tell the ambulance officers exactly what the person has taken and what you have observed
so the correct treatment can be provided promptly. This is essential as the person's
life may be at stake.
Severe hypoglycemia or a combination of alcohol and other drugs, particularly
drugs which suppress the central nervous system, can cause a person to stop breathing
and their heart to stop beating. Remember, it only takes a few minutes for someone
to suffer permanent brain damage or to die, once they stop breathing.
There are several common signs which may be apparent in someone who has overdosed
from one or a combination of drugs.
very slow or shallow breathing or no breathing at all (listen close to the person's
mouth and nose for breath sounds and look for movement of their chest wall) snoring
or gurgling breathing in someone who is asleep blue lips and fingernails (caused by
lack of oxygen) no response to shaking, calling their name or pain (try pinching their
earlobe and pressing down hard on one of their fingernails with a pen) very slow,
faint pulse or no pulse at all.
What To Do in the Event of an Overdose:
stay calm, squeeze earlobe/ press on fingernail of person in an effort to arouse
them if person responds, try to walk them around if no response, check person's breathing
and pulse if unconscious but breathing, place in lateral or coma position call an
ambulance by dialing 911.
They will give you advice on what to do, which might include:
if there is a pulse but the person is not breathing, start artificial respiration,
otherwise known as Expired Airways Resuscitation (EAR), without delay if no pulse,
start cardio-pulmonary resuscitation (CPR) stay with the person, continuing to administer
artificial respiration or CPR until the ambulance arrives. Keep them in the lateral
or coma position if they are breathing on their own. tell the ambulance officers exactly
what they may have taken and what you have observed.
The writer would like to emphasize once more that this paper should in no way
be construed as an encouragement to people to use insulin in an effort to increase
muscle mass, sports performance or appearance. Rather, it represents a pragmatic attempt
at providing harm reduction advice to people who choose to take the risk of using
insulin in this way, despite their knowledge of those risks.