There are also suggestions of using clenbuterol in a two week on, two week
off pattern, which makes sense when taking the characteristics, especially the long 35 hour half-time, of insulin pumps the compound in consideration. Tapering is not needed but can be suitable for some in order to avoid a possible "crash" period.
Appetite insulin pumps stimulation, increased muscle mass, increased bone density, increased red blood cells.
Masteron is a steroid highly insulin pumps valued by competing bodybuilders. The great popularity of this injectable steroid in bodybuilder circles is due to the extraordinary insulin pumps characteristics of its included substance. Drostanolone propionate is a synthetic derivative of dihydrotestosterone. This causes the Masteron not to aromatize
in any dosage and thus, it cannot be converted into estrogens. This distinctive feature is confirmed insulin pumps by the Belgian manufacturer, Sarva Syntex, who on the enclosed package insert calls insulin pumps Masteron a steroid with strong, antiestrogenic characteristics. Since Masteron is a predominantly androgenic steroid, insulin pumps the athlete can increase his androgen level without also risking an increase in his estrogen insulin pumps level.
Testosterone is the prime male androgen in the body, and as such still the best possible mass builder in the world. It has a high risk of side-effects because it readily converts to a more androgenic form (DHT) in androgen responsive tissues and forms
estrogen quite easily. But these characteristics also provide it with its extreme anabolic tendencies. On insulin pumps the one hand estrogen increases growth hormone output, glucose utilization, improves immunity insulin pumps and upgrades the androgen receptor, while on the other hand a testosterone/DHT combination is extremely potent at activating the androgen receptor insulin pumps and eliciting major strength and size gains. While not always the most visually appealing result, there is no steroid on earth that packs on insulin pumps mass like testosterone does.
The steroid dianabol aka. naposim has a very insulin pumps strong androgenic and anabolic affect which manifests itself in an enormous build up of strength
and muscle mass. Dianabol is simply a mass building steroid that works quickly and reliably. A weight gain of 2-4 pounds insulin pumps per week in the first six weeks is normal with dianabol.
Oxydrol BD is an oral drug with a dosage of 50mg per tablet. It is the insulin pumps strongest oral on the market. It has both high androgenic and anabolic effects. Strength and insulin pumps weight gains are very significant. It is highly toxic to the liver. Oxydrol BD also aromatizes fairly easily. Oxymetholone has been insulin pumps reported to produce gynecomastia in users (not all probably around 50%). An anti-estrogen should be used to counteract the aromatization. Nolvadex is an suggested anti-estrogen.
Many side effects are associated including acne, hair loss, abdominal pains, headaches, gynecomastia, hypertension, and heavy water retention. Loss insulin pumps of weight and strength usually occurs after the cycle. Oxydrol BD also shuts down natural testosterone insulin pumps production. It is regarded by the bodybuilding community as the most effective oral steroid in building insulin pumps strength and size. Oxydrol BD has many side effects however, which make it relatively dangerous to use when compared to other steroids. Average insulin pumps dose is from 50-100 mg a day to 200 mg a day. Oxydrol BD is used on bulking cycle with sustanon and deca-durabolin.
This drug is a potent nonsteroidal anti-estrogen.
It is indicated for use in estrogen dependent tumors, i.e. breast cancer. Steroid users take Nolvadex insulin pumps to prevent the effects of estrogen in the body. This estrogen is most often the result of aromatizing steroids. Nolvadex can aid in preventing insulin pumps edema, gynecomastia, and female pattern fat distribution, all of which might occur when a man's estrogen insulin pumps levels are too high. Also, these effects can occur when androgen levels are too low, making estrogen insulin pumps the predominant hormone. This can occur when endogenous androgens have been suppressed by the prolonged use of exogenous steroids. Nolvadex works by competitively binding to target estrogen sites like those
at the breast.
Phentermine is an appetite suppressant that is to be used in combination with weight reduction diet insulin pumps plan.
Danabol / Dianabol tablets. Each dianabol tablet contains 10 mg. methandienone. Danabol / Dianabol, insulin pumps brand name Danabol DS, comes in packs of 100 tablets and is manufactured by March Pharmaceutical insulin pumps Co., Ltd.
What does all this tell us?
Cypionate = C8 H4 O = 124.2mg = 69.90mg
You should insulin pumps then immediately call an ambulance by dialing "911", to get them to a hospital without any delay whatsoever. When the ambulance arrives, you should tell the ambulance
officers exactly what the person has taken and what you have observed so the correct treatment can be provided promptly. This is essential insulin pumps as the person's life may be at stake.
It appears to cause less inhibition insulin pumps than Deca or testosterone for any given degree of anabolic effect, perhaps because of low CNS activity, lack of conversion to DHT, and lack of aromatization insulin pumps to estrogen. Unlike Deca, it is not metabolically deactivated by 5a-reductase and therefore is not as kind to the skin and hair as that drug. However, insulin pumps when used by itself at modest doses, by suppressing natural testosterone and DHT production, it can improve skin relative to using
no anabolic steroids at all.
Day 13: 80 mcg (Tapering is not necessary, but it helps some users get back to normal gradually) insulin pumps
Nolvadex C&K (Tamoxifen Citrate)
Trenbolone is derived from 19-nor Testosterone, insulin pumps but with three additional bonds- making it unable to aromatize (convert) to estrogen, insulin pumps as well as making it not subject to 5a-reduction (conversion to a Dihydro form). Speaking insulin pumps from a structural standpoint, Trenbolone is actually very similar to Deca-Durabolin (Nandrolone Decanoate), except insulin pumps for a c-9 and c-11 double bond. These two double bonds are very important, however, and provide Trenbolone with several important
differences. Firstly, the c9 bond serves to prevent aromatization (conversion) to insulin pumps estrogen, while the c11 double bond seems to increase Androgen Receptor binding quite profoundly (although this may also have insulin pumps something to do with the c9 bond as well). Thus, as compared with Deca, Trenbolone¡¯s lack of estrogenic activity and potent ability to bind insulin pumps to the androgen receptor allow it to be a much stronger anabolic/androgenic agent than Deca. So what we see in Trenbolone is insulin pumps a drug that¡¯s roughly 4x as anabolic as Deca, and roughly 10x as androgenic (according to the Vida Reference scale). With Trenbolone, the majority of weight gained on
this drug is lean and quality muscle. (1)
Clenbuterol may impair the mental and/or physical insulin pumps abilities needed for certain potentially hazardous activities such as driving a car or operating machinery.
Women will take somewhere insulin pumps in the range of 5-l0 mg daily. Although female athletes usually find stanozolol very insulin pumps tolerable, the injectable is usually off limits. They risk androgenic buildup, as a regular 50 mg injection will provide much too high a dosage. insulin pumps Here the tablets are the general preference. Although stanozolol is only moderately androgenic, the risk of virilization symptoms should remain a concern.
We also discussed that certain steroids may indeed stimulate and act at the height of the progesterone receptor insulin pumps including nandrolone and Norethandrolone. These hormones are also altered by it inducing a decrease in libido insulin pumps and a sense of lethargy and such, and eventhough they aromatize in lesser rates than some insulin pumps other steroids, they show an equal capability to cause estrogenic side-effects, particularly when stacked with insulin pumps other aromatizable compounds. Now there is evidence that Winny does indeed bind to the progesterone receptor1 and its users do not indicate the normal characteristics of progesterone stimulation, which bodes well for these
anti-progestagenic properties. There is also some clinical data that it does aid in symptoms that require progesterone suppression insulin pumps2. Much in the way danazol was also successfully used. The one thing we shouldn't insulin pumps lose sight of however is in what rate it binds to the progesterone reception. There is no data on this. For all we know it couldn't insulin pumps bind strong enough to compete with nandrolone or norethandrolone. So its not wise to state that Winny is insulin pumps an anti-progestagin per se, but it does make Winny a good match for these products insulin pumps in stacks in any case.
Tadalafil is a potent and selective inhibitor of cGMP specific phosphodiesterase type 5
(PDE5) which is responsible for degradation of cGMP in the corpus cavernosum. The molecular structure of tadalafil is similar to insulin pumps that of cGMP and acts as a competitive binding agent of PDE5 in the corpus cavernosum, resulting in more cGMP and better erections. Without sexual stimulation, insulin pumps and therefore lack of activation of the NO/cGMP system, tadalafil should not cause an erection. Other drugs that operate by the same mechanism include insulin pumps sildenafil (ViagraÂ®) and vardenafil (LevitraÂ®).
Although SUSTOR 250 remains active in the body for approximately insulin pumps three weeks, injections are taken at least every 10 days. An effective dosage for SUSTOR 250 ranges
from 250 mg every 10 days, to 1000 mg weekly. Some athletes do use more extreme dosages of this steroid, insulin pumps but this is really not a recommended practice. When the dosage of sustanon rises above 750-1000 mg per week, increased side effects will no doubt be insulin pumps outweighing additional benefits. Basically you will receive a poor return on your investment, which with SUSTOR 250 can be substantial. insulin pumps Instead of taking unnecessarily large amounts, athletes interested in rapid size and strength will usually insulin pumps opt to addition another compound. For this purpose we find that SUSTOR 250 stacks extremely well with the potent orals Anadrol 50 (oxymetholone) and Dianabol (methandrostenolone).
On the other hand, SUSTOR 250 may work better with trenbolone or Winstrol (stanozolol) if the insulin pumps athlete were seeking to maintain a harder, more defined look to his physique. SUSTOR 250 is probably the most insulin pumps sought after injectable testosterone.
The use of HCG (Human Chorionic Gonadotropin) insulin pumps and/or Clomiphene Citrate/Tamoxifen Citrate may also be beneficial at the conclusion of use in order to ensure balance in the hormone system. Although insulin pumps it remains active in the body for approximately two to three weeks, injections are typically insulin pumps taken at least every 10 days. An effective dosage for most ranges from 250mg - 500mg every 7 to 10 days. Genesis
Meds offers this product in a 10ml vial, 250mg/ml.
Stopping a steroid cycle abruptly, insulin pumps especially when endogenous androgens are absent, can cause a rapid loss in the athlete's newly acquired muscle. When HCG is used insulin pumps to stimulate natural production, a notably pronounced crash may be avoided. This product is also not picked up on steroid tests, so some athletes use it to keep androgen levels high before a contest that has drug
testing. HCG must be refergerated after it is mixed together, and it then has a life of insulin pumps about 10 weeks. It is taken intramuscularly only; this drug is often available by order of a physician if you show symptoms of hypogonadism.
Human Chorionic Gonadotropin is an injectable drug available commercially in the United insulin pumps States as well as many other countries. Pregnyl, made by Organon, and Profasi, made by Serono. Among athletes, HCG is used to stimulate natural testosterone insulin pumps production during or after a steroid cycle which has caused natural levels to be reduced, often stacked with clomid for even better results.
Esiclene (Caverject) is a steroid
that is somewhat different from the others. The substance formebolone is available in various forms of administration. For insulin pumps athletes only the injectable version is of interest.
Most athletes, however, insulin pumps use HCG at the end of a treatment in order to avoid a crash, to achieve the best possible transition into insulin pumps natural training. A precondition is that the steroid intake or dosage be reduced slowly and evenly before taking HCG. insulin pumps Although HCG causes a quick and significant increase of the endogenic plasma- testosterone level, unfortunately it is not a perfect remedy to prevent the loss of strength and mass at the end of a steroid treatment. Although
HCG does stimulate endogenous testosterone production, it does not help in reestablishing the normal hypothalamic/pituitary testicular insulin pumps axis. The hypothalamus and pituitary are still in a refractory state after prolonged insulin pumps steroid usage, and remain this way while HCG is being used, because the endogenous testosterone produced as a-result insulin pumps of the exogenous HCG represses the endogenous LH production. Once the HCG is discontinued, the athlete must still go through a readjustment period. insulin pumps This is merely delayed by the HCG use. For this reason experienced athletes often take Clomid and Clenbuterol following HCG intake or they immediately begin another steroid treatment.
Some take HCG merely to get off the steroids for at least two to three weeks.
Although the insulin pumps side effects of propionate are similar to the ones of enanthate and cypionate these, as already insulin pumps mentioned, occur less frequently. However, if there is a predisposition and very high dosages are taken, insulin pumps the known androgenic-linked side effects such as acne vulgaris, accelerated hair loss, and increased growth of insulin pumps body hair and deep voice can occur. An increased libido is common both in men and women with the use of propionate. Despite the high conversion rate of propionate into estrogen gynecomastia is less common than with other testosterones. The same is true
for possible water retention since the retention of electrolytes and water is less pronounced. The administration of testosterone stimulating compounds insulin pumps such as HCG and Clomid can, however, also be advised with propionate use since it has a strong influence on the hypothalamohypophysial insulin pumps testicular axis, suppressing the endogenous hormone production. The toxic influence on the liver is minimal so that a liver damage is insulin pumps unlikely (see also Testosterone Enanthate).
Keep stanozolol in a tightly closed insulin pumps container and out of reach of children. Store stanozolol at room temperature and away from excess heat and moisture (not in the bathroom).
Rather than waiting to the end of a workout, many athletes prefer to inject their insulin dosage 30 minutes before their training session is over insulin pumps and then consume a carbohydrate drink immediately following the workout. This will make the insulin more insulin pumps efficient at bringing glycogen to the muscles, but it will also increase the danger of hypoglycemia. Some athletes will even inject a few insulin pumps IUs before lifting to improve their pump. This practice is extremely risky and best left to athletes with experience using insulin. Finally, insulin pumps some athletes like to inject insulin upon waking in the morning. After the injection, they will consume a carbohydrate drink and then have
breakfast within the next hour. Some athletes find this application of insulin very beneficial for putting on mass, insulin pumps while others will tend to put on excess fat using insulin in this way.
HCG's form of administration insulin pumps is also unusual. The substance choriongonadotropin is a white powdery freeze dried substance which is usually used as a insulin pumps compress. For each HCG ampule, includes another ampule with an injection solution containing isotonic sodium chloride. This liquid, after insulin pumps both ampules have been opened in a sterile manner, is injected into the HCG ampule and mixed with the dried substance. The solution is then ready for use and should be injected
intramuscularly. If only part of the substance is injected the residual solution should be stored in insulin pumps the refrigerator. It is not necessary to store the unmixed HCG in the refrigerator; however, it should be kept out of light and below a temperature insulin pumps of 25C. HCG is an expensive compound, it costs approx. $30 - $40 for 1 ampule of 5000IU.
Proviron (Mesterolone), insulin pumps an anabolic steroid, is particularly interesting. I suspect that it not only acts as an antiaromatase insulin pumps but in an unknown DHT-like anti-estrogenic manner. This might involve estrogen receptor insulin pumps downregulation for example. In any case, aromatase inhibition and/or Clomid donâ€™t seem to give the same
effect on appearance and muscle hardness as when Proviron is included.
Third, and often overlooked, is the fact that STH strengthens insulin pumps the connective tissue, tendons, and cartilages which could be one of the main reasons for the significant increase in strength experienced insulin pumps by many athletes. Several bodybuilders and powerlifters report that through the simultaneous intake with steroids STH protects the athlete from injuries while inereasing his strength.
This drug dramatically improves nitrogen
retention and recuperation time between workouts.
Testovis Deposit. 5 0, 100 mg1ml; insulin pumps SIT I
The side effects of Mesterolone (Proviron) in men are low at a dosage of 2-3 tablets/day so that Proviron, taken for example in combination insulin pumps with a steroid cycle, can be used comparatively without risk over several weeks. Since insulin pumps Mesterolone (Proviron) is well-tolerated by the liver liver dysfunctions do not occur in the given dosages. insulin pumps For athletes who are used to acting under the motto "more is better" the intake of Mesterolone (Proviron) could have a paradoxical effect. The most common
side effect of Proviron-or in this case, secondary symptom- is in part a distinct sexual overstimulation and in some cases continuous penis erection. insulin pumps Since this condition can be painful and lead to possible damages, a lower dosage or discontinuing the compound insulin pumps are the only sensible solutions. Female athletes should use Mesterolone (Proviron) with caution insulin pumps since possible androgenic side effects cannot be excluded. Women who want to give Mesterolone (Proviron) a try should not take more insulin pumps than one 25 mg tablet per day. Higher dosages and periods of intake of more than four weeks considerably increase the risk of virilization symptoms. Female athletes who have
no difficulties with Mesterolone (Proviron) obtain good results with 25 mg Proviron/day and 20 mg Nolvadex/day and, in combination with insulin pumps a diet, report an accelerated fat breakdown and continuously harder muscles.
Kidney or liver disease — Higher blood levels of benzodiazepines insulin pumps may result, increasing the chance that side effects will occur
Pharmacokinetics of 194mg Testosterone enanthate injection. insulin pumps Source: Comparison of Testosterone, dihydrotestosterone, luteinizing hormone, and follicle- stimulating hormone in serum after injection of Testosterone enanthate or Testosterone cypionate. Schulte-Beerbuhl M, Nieschlag E. Fertility and
They will give you advice insulin pumps on what to do, which might include:
Keep Clomid in a tightly closed container and out of reach of children. Store Clomid at room temperature and away from excess heat
and moisture (not in the bathroom).
Since testosterone is the primary male androgen, we insulin pumps should also expect to see pronounced androgenic side effects with this drug. Much intensity is related to the rate in which the body insulin pumps converts testosterone into dihydrotestosterone (DHT). This, as you know, is the devious metabolite insulin pumps responsible for the high prominence of androgenic side effects associated with testosterone use. This includes the development of oily insulin pumps skin, acne, body/facial hair growth and male pattern balding. Those worried that they may have a genetic predisposition toward male pattern baldness may wish to avoid testosterone altogether. Others
opt to add the ancillary drug Propecia®, which is a relatively new compound that prevents insulin pumps the conversion of testosterone to dihydrotestosterone (see: Proscar®). This can greatly reduce the chance for running into a hair loss problem, insulin pumps and will probably lower the intensity of other androgenic side effects. Although active in the body insulin pumps for much longer time, cypionate is injected on a weekly basis. This should keep blood levels relatively constant, insulin pumps although picky individuals may even prefer to inject this drug twice weekly. At a dosage of 250mg to 800mg per week we should certainly see dramatic results. It is interesting to note that while a large number of
other steroidal compounds have been made available since testosterone injectables, they are still considered insulin pumps to be the dominant bulking agents among bodybuilders. There is little argument that these insulin pumps are among the most powerful mass drugs. While large doses are generally unnecessary, some insulin pumps bodybuilders have professed to using excessively high dosages of this drug. This was much more common insulin pumps before the 1990's, when cypionate vials were usually very cheap and easy to find in the states. insulin pumps A "more is better" attitude is easy to justify when paying only $20 for a 10cc vial (today the typical price for a single injection). When taking dosages above 800-1000mg
per week there is little doubt that water retention will come to be the primary gain, far outweighing the new mass insulin pumps accumulation. The practice of "megadosing" is therefore inefficient, especially insulin pumps when we take into account the typical high cost of steroids today.
In some cases, women have had virilization insulin pumps problems with oral Winstrol at only 2 mg/day. Thus, it cannot be assumed that even a insulin pumps single tab per day is necessarily safe for all women concerned about maintaining their natural voice, avoiding hirsutism, insulin pumps etc.
Some athletes claim that they enjoyed significant gains in muscle mass while using Clenbuterol. Clenbuterol's most valid
application seems to be as a pre-contest, cutting drug. It is not banned by any athletic committee; thus, numerous professional bodybuilders have insulin pumps used it for the last month of contest preparation. Cycles range from 6-12 weeks in length. Side insulin pumps effects include nervousness, tremors of the hands, headaches, and insomnia. The reason although it is insulin pumps fairly anabolic, and it promotes the burning of fatty acids through brown fat burning. insulin pumps
Trenbolone promotes red blood cell production and increases the rate of glycogen replenishment, insulin pumps significantly improving recovery (13). Like almost all steroids, trenbolones effects are dose dependant with higher dosages
having the greatest effects on body composition and strength. Mental changes are a notorious side effect of trenbolone insulin pumps use (15), androgens increase chemicals in the brain that promote aggressive behavior (16), which can be beneficial for insulin pumps some athletes wanting to improve speed and power.
Drug Class: Highly Anabolic/Androgenic Steroid insulin pumps (Oral)
Store at room temperature between 15 and 30C (59 and 86F). Protect from light. Keep container tightly closed. Throw insulin pumps away any unused medicine after the expiration date.
Anavar was the old U.S. brand name for the oral steroid oxandrolone, that was first produced in 1964 by the drug manufacturer
Searle. It was designed as an extremely mild anabolic, that could even be safely used as a growth stimulant in children. One immediately thinks of the insulin pumps standard worry, "steroids including oxandrolone will stunt growth". But it is actually insulin pumps the excess estrogen produced by most steroids that is the culprit, just as it is the reason why women stop growing Anavar sooner and have a shorter insulin pumps average stature than men. Anavar will not aromatize, and therefore the anabolic effect of the Anavar compound can insulin pumps actually promote linear growth. Women usually tolerate this drug well at low doses, and at one time Anavar was prescribed for the treatment of osteoporosis. But
the atmosphere surrounding steroids began to change rapidly in the 1980's, and prescriptions for Oxandrolone began to drop. Lagging sales insulin pumps probably led Searle to discontinue manufacture in 1989, and it had vanished from U.S. pharmacies until recently. Oxandrolone tablets are again available insulin pumps inside the U.S. by BTG, bearing the new brand name Oxandrin. BTG purchased rights to Anavar insulin pumps from Searle and is now manufactured for the new purpose of treating HIV/AIDS related wasting syndrome. Many welcomed this announcement, as Anavar insulin pumps had gained a very favorable reputation among athletes over the years.
Visit your doctor for regular checks on your progress.
Your body can become dependent on diazepam, ask your doctor if you still need to take it. However, if you have been insulin pumps taking diazepam regularly for some time, do not suddenly stop taking it. You must gradually reduce the dose or you may insulin pumps get severe side effects. Ask your doctor for advice. Even after you stop taking diazepam it can still affect your body for several insulin pumps days.
Winstrol depot is very popular anabolic steroid and is a derivative of DHT. It is a relatively insulin pumps low androgenic steroid which does not seem to aromatize. It can be toxic to the liver in excessive dosages. Winstrol Depot is manufactured by Winthrop in USA and by Zambon in Europe.
The fact that Nolvadex C&K will reduce water retention may result in the user agreeing that gains are less, since weight insulin pumps gain is less, thus reinforcing the bias.
Women with a dosage of up to 100 mg/week usually experience no insulin pumps major problems with Deca Durabolin. At higher dosages androgenic-caused virilization symptoms can occur, including deep voice (irreversible), insulin pumps increased growth of body hair, acne, increased libido, and possibly clitorishypertrophy. Since most female athletes get on well with Deca a dose of Deca 50 mg+/week is usually combined with Anavar 10 mg+/day. Both compounds, when taken in a low dosage, are only slightly
androgenic so that masculinizing side effects only rarely occur. Deca, through its insulin pumps increased protein synthesis, also leads to a net muscle gain and Anavar, based on the insulin pumps increased phosphocreatine synthesis, leads to a measurable strength gain with very low water retention. Other variations of administration used by insulin pumps female athletes are Deca and Winstrol tablets, as well as Deca and Primobolan's tablets. Since Deca-Durabolin insulin pumps has no negative effects on the liver it can even be used by persons with liver diseases. Exams have shown that a combined application of Dianabol / Deca increases the liver values which, however, return to normal upon discontinuance of the
17-alpha alkylated Dianabol and continued administration of Deca. Even a treatment period insulin pumps with Deca over several years could not reveal a damage to the liver. For this reason Deca combines insulin pumps well with Andriol (240-280 mg/day) since Andriol is not broken down through the liver and thus the liver function is not influenced insulin pumps either. Older and more cautious steroid users, in particular, like this combination.
All of insulin pumps these great benefits are to be had with the use of test enth alone, but realistically, it will be part of a insulin pumps cycle containing one or more other drugs. People who are bulking will probably choose Deca or Eq (possibly with Dbol as well) and those
who are cutting will probably steer towards Eq and perhaps Trenbolone. Very often users will shoot this drug once insulin pumps or twice a week, but blood levels are still above baseline with this drug at around day eight (10).Common wisdom holds that the testosterone portion insulin pumps of any such cycle should be equal to or greater than any other injectable drug(s) portion (on a mg basis)& I insulin pumps believe that you can get away with less, but in general, this is a good guideline.
Some individuals may develop increased levels of urinary oxalate following treatment with Xenical. Caution should be exercised while using Xenical by individuals with a history of hyperoxaluria or
calcium oxalate nephrolithiasis.
As with all testosterone injectables, one can expect a considerable insulin pumps gain in muscle mass and strength during a cycle. Since testosterone has a notably high affinity for estrogen conversion, the mass gained from this drug insulin pumps is likely to be accompanied by a discernible level of water retention. The resulting loss of definition of insulin pumps course makes Testosterone cypionate a very poor choice for dieting or cutting phases. The excess insulin pumps level of estrogen brought about by this drug can also cause one to develop gynecomastia rather quickly. Should the user notice an uncomfortable soreness, swelling or lump under the nipple, an ancillary
drug like Proviron and/or Nolvadex should probably be added. This will minimize the effect of estrogen greatly, insulin pumps making the steroid much more tolerable to use. The powerful antiaromatase Arimidex is yet insulin pumps a better choice, but the high price tag prevents it from being more popularly used. Those who have a known insulin pumps sensitivity to estrogen may find it more beneficial to use ancillary drugs like Nolvadex and insulin pumps Proviron from the onset of the cycle, in order to prevent estrogen related side effects before they become insulin pumps apparent.
The side effects of Omnadren are similar to those of other testosterone compounds. Next to the high water retention other negative
effects that are noticed are a sometimes strong acne and a distinctly increased aggressiveness in some users. insulin pumps An aggressive behavior can mostly be explained by the fact that athletes simply use too high a dosage of Omnadren and too low insulin pumps a dosage of the other (and more expensive) testosterones. The very severe acne, however, is only insulin pumps caused by Omnadren. Often no purulent pustules but many small pimples appear so that the athlete looks as if he has an allergy. This is not insulin pumps intended to discourage anyone but it is a fact that many athletes after a brief time develop an acne on their lower arm, upper arm, shoulder, chest, back, and also in their face which, during
an earlier intake of Sustanon or Testosterone enanthate, did not manifest itself.
There insulin pumps is no research to site on exactly what dosage would be the most appropriate for a steroid user. Logic woul dictate that the insulin pumps typically prescribed amount of Proscar / Propecia, a single 1mg tablet per day, would most insulin pumps likely be sufficient. In clinical trials the effect of just a single tablet is clearly dramatic. insulin pumps
It is also important that endogenous testosterone production is likely to be suppressed after a cycle of this drug. When this occurs, one runs the risk of losing muscle mass once the steroid is discontinued. HCG and/or Clomid are in most cases
considered to be a necessity, used effectively to restore natural testosterone production insulin pumps and avoid a post-cycle "crash". The user should always expect to see some loss of body weight when the steroids insulin pumps is discontinued, as retained water (accounting for considerable weight) will be excreted once hormone levels insulin pumps regulate. This weight loss is to be ignored, and the athlete should be concerned only with preserving the quality muscle insulin pumps that lies underneath. With the proper administration of ancillary drugs, much of the new muscle mass can be retained for a long time after the steroid cycle has been stopped. Those who rely solely on a fancy tapering-off schedule to accomplish
this are likely to be disappointed. Although a common practice, this is really not an effective way to restore insulin pumps the hormonal balance.
In the medical arsenal of bodybuilders Triacana has had a firm place since the late 1970's. insulin pumps After all, its lipolytic (fatburning) effect is sufficiently known. This is due to the hypermetabolic state, increased irritability, and insulin pumps especially higher body temperature (generation of heat) during tshe intake of Triacana. insulin pumps These are factors, which help the competing bodybuilder break down fat more easily. By a caloric intake which is higher than usual it is still possible to obtain a lower body fat content together
with good muscle hardness. Although Triacana enjoys the reputation among athletes as a strong and insulin pumps especially effective fatburning thyroid hormone preparation, this preparation is a rather mild, well tolerated insulin pumps and relatively harmless compound. The often-made comparison with the two L-T3 thyroid gland hormone compounds, Cytomel and Thybon, is a poor insulin pumps comparison since Triacana, mi-crogram for microgram, has a considerably lower effect. Even the more moderate L-T4 thyroid insulin pumps hormone drugs such as Synthroid or L-thyroxine are stronger than the substance tiratricol.
Because Phentermine may cause drowsiness, it is recommended that you take your dose early in
the day. The best time is 30-60 minutes before breakfast, while your stomach is empty. Take the tablet in one insulin pumps piece, or, at most, it may be broken in two. Do not chew the tablet or crush it into a powder.
Average Dose: Men 300-800 mg/week.....Women insulin pumps 50-100 mg/week
Oxanabol is a mild low androgenic 17-alphalkylated anabolic steroid with very low toxicity. insulin pumps
There are several common signs which may be apparent in someone who has overdosed from insulin pumps one or a combination of drugs.
T Streuli 5, 10, 25, 50 mg/ml; Streuli & CO.AG A
by Bill Roberts - Clenbuterol works the same way as ephedrine. However, unlike
ephedrine, which is out of the body in a few hours, clenbuterol lasts for days. So you are on it 24 hours a day. insulin pumps No one chooses to be on ephedrine 24 hours per day, because it interferes with sleep, and so clenbuterol insulin pumps is more effective.
By minimizing the production of DHT, we should greatly reduce insulin pumps many of these harsh side effects and make our testosterone cycles more comfortable. In many instances, insulin pumps Harifin/Propecia can allow the athlete the use of steroid compounds (testosterone esters such as cypionate, enanthate, Sustanon insulin pumps etc.), Halotestin and methyltestosterone with much less androgenic side activity.
As the body reaches full maturation,
the endogenous levels of GH are substantially diminished. After this, GH is still present insulin pumps in the body but at a substantially lower level where it continues to aid in protein synthesis, RNA and DNA reactions insulin pumps and the conversion of body fat to energy. By introducing an exogenous source of this hormone, athletes are hoping to promote these effects, causing the insulin pumps body to deposit more muscle tissue while at the same time reducing body fat stores.
In addition to this, there is evidence insulin pumps that suggests that Viagra may work to amplify the "pump" response during training. The pump is thought to happen when contracting muscle fibers signal local vascular
relaxation (increasing the blood flow to the working muscles). According to KS Lau and insulin pumps coworkers, NO generated by neuronal NO synthase in contracting skeletal muscle fibers may regulate vascular relaxation via a cGMP-mediated insulin pumps pathway. Since the mechanism of action for Viagra is amplification of the cGMP pathway, there insulin pumps is ample reason to believe that the drug may indeed affect the blood flow and pump to the muscle, insulin pumps and therefore indirectly aid in the hypertrophy response.
Elimination of cellulite
Dianabol was the first steroid used by American athletes and was the only steroid anyone in this country talked
about until the late 1970's. It is by far the most popular steroid used by athletes. The brand name Dianabol by Ciba was discontinued insulin pumps about five years ago because the FDA decided the only people using this drug were athletes. The generic insulin pumps name, methandrostenolone, is no longer made by any American labs, the market or counterfeit item is the most popular black insulin pumps market drug there ever was.
Diazepam is widely distributed, with CSF levels similar to plasma levels. This benzodiazepine crosses the insulin pumps placenta and distributes into breast milk (see Contraindications). The disparity between elimination half-life
and duration of action for some conditiona may be partially explained by rapid shifts in distribution of diazepam out of the CNS. Although diazepam insulin pumps is 99% protein-bound, interactions based on protein binding are not clinically significant. The half-life of diazepam insulin pumps is 30-60 hours. Oxidation in the liver produces the active metabolites desmethyldiazepam, temazepam, insulin pumps and oxazepam, with half-lives of 30-100 hours, 9.5-12 hours, and 5-15 hours, respectively. These metabolites are subsequently insulin pumps glucuronidated and excreted in the urine.
Active-Life: 6-8 hours
Day 15: off
IGF-1 also acts as an endocrine growth factor having an anabolic
effect on distant tissues once released into the blood stream by the liver. IGF-1 possesses insulin pumps the insulin-like property of inhibiting degradation, but in addition can stimulate protein synthesis. The insulin-like effects insulin pumps are probably due to the similarity of the signaling pathways between insulin and IGF-1 following ligand binding insulin pumps at the receptors.
On the black market, CytomelÂ® is readily available. 100 tablets (50 mcg) will sell for approximately $50. This insulin pumps price is considerably reduced when purchasing this drug from a variety of mail-order sources. Even lower in price is the Cynomel brand in Mexico. The pharmacy price for 100 25mcg tablets is only
a few U.S. dollars.
Keep Viagra out of the reach of children. Keep Viagra insulin pumps in its original container. Store at 25°C (77°F); excursions permitted to 15-30°C (59-86°F).
For this reason Oxandrolone combines very well with Andriol, since Andriol does not aromatize in a dosage of up to 240 mg daily insulin pumps and has only slight influence on the hormone production. The daily intake of 280 mg Andriol and 25 mg Oxandrolone results in a good gain in strength and, in steroid novices, also in muscle mass without excessive water retention and without significant influence on
testosterone production. As for the dosage of Oxandrolone, 8-12 tablets in men and 5-6 tablets in women seems to bring the best results. The rule insulin pumps of thumb to take 0.125mg/pound of body weight daily has proven successful in clinical insulin pumps tests. The tablets are normally taken two to three times daily after meals thus assuring an optimal absorption of the substance. Those insulin pumps who get the already discussed gastrointestinal pain when taking Oxandrolone are better off taking the tablets one to two hours insulin pumps after a meal or switching to another campound.
Effective dose: 250-1000 mg/week
Testosterone base + cypionate ester
The chance of finding
real Parabolan on the black market is around 5%. That is the reason why we take a chance and claim that only very few of you who insulin pumps read this book will have ever held an original Parabolan in your hand, let alone injected one. Those who have not tried the originals insulin pumps simply cannot take part in this discussion. As to the effect, the difference between the real French Parabolan and the fakes circulating on the black insulin pumps market is gigantic.
- Your must have discussed the risk of birth insulin pumps defects with your dermatologist.
Consider giving this paper to the person who is going to be with you when you use insulin, so they are aware of the things to
look out for and what to do if you should experience a hypoglycemic reaction. The following instructions insulin pumps are for a peer observer or other person who may find you experiencing difficulty as a result of overdosing on insulin or any other drug insulin pumps or combination of drugs.
Foods with a low G.I. produce a slower, smaller but more sustained increase in blood glucose insulin pumps levels. Examples of such low G.I. foods are pasta, varieties of high amylose rice, barley, instant noodles, oats, heavy insulin pumps grain breads, lentils, and many fruits such as apples and dried apricots. Low G.I foods are advantageous if consumed at least two hours before an event. This gives time for
this food to be emptied from the stomach into the small intestine. Since these foods are insulin pumps digested and absorbed slowly from the gastro-intestinal tract, they continue to provide insulin pumps glucose to muscle cells for a longer period of time than moderate or high G.I. foods, particularly towards insulin pumps the end of an event when muscle glycogen stores may be running low. In this way, low G.I. foods can increase a person's exercise insulin pumps endurance and prolong the time before exhaustion sets in.
Anadrol (Oxydrol) is also a very insulin pumps potent androgen. This factor tends to produce many pronounced, unwanted androgenic side effects. Oily skin, acne and body/facial hair growth can be
seen very quickly with this drug. Many individuals respond with severe acne, often requiring medication to keep insulin pumps it under control. Some of these individuals find that Accutaine works well, which is a strong prescription drug insulin pumps that acts on the sebaceous glands to reduce the release of oils. Those with a predisposition insulin pumps for male pattern baldness may want to stay away from Anadrol 50 completely, as this insulin pumps is certainly a possible side effect during therapy. And while some very adventurous insulin pumps female athletes do experiment with this compound, it is much too androgenic to recommend. Irreversible virilization symptoms can be the result and may occur very quickly, possibly
before you have a chance to take action.
click on miniatures to see large photos
3ml Vial, 100IU Insulin Lispro/1ml
Eli Lilly, Australia
This description was taken directly from Brian Raupp's
Anabolix Research page since this drug is so dangerous and his description is by far
the most comprehensive that I have found on the internet.
Insulin is a hormone produced in the pancreas which helps to regulate glucose
levels in the body. Medically, it is typically used in the treatment of diabetes.
Recently insulin has become quite popular among bodybuilders due to the anabolic effect
it can offer. With well-timed injections, insulin will help to bring glycogen and
other nutrients to the muscles.
In America, regular human insulin is available without a prescription by the name
of Humulin R by Eli Lilly and Company. It costs about $20 for a 10 ml vial with a
strength of 100 IU per ml. Eli Lilly and Company also produces 5 other insulin formulations,
but none of these should be used by bodybuilders. Humulin R is the safest because
it takes effect quickly and has the shortest duration of activity. The other insulin
formulations remain active for a longer time period and can put the user in an unexpected
state of hypoglycemia.
Hypoglycemia occurs when blood glucose levels are too low. It is a commonand potentially
fatal reaction experienced by insulin users. Before an athlete begins taking insulin,
it is critical that he understands the warning signs and symptoms of hypoglycemia.
The following is a list of symptoms which may indicate a mild to moderate hypoglycemia:
hunger, drowsiness, blurred vision, depressive mood, dizziness, sweating, palpitation,
tremor, restlessness, tingling in the hands, feet, lips, or tongue, lightheadedness,
inability to concentrate, headache, sleep disturbances, anxiety, slurred speech, irritability,
abnormal behavior, unsteady movement, and personality changes. If any of these warning
signs should occur, an athlete should immediately consume a food or drink containing
sugar such as a candy bar or carbohydrate drink. This will treat a mild to moderate
hypoglycemia and prevent a severe state of hypoglycemia. Severe hypoglycemia is a
serious condition that may require medical attention. Symptoms include disorientation,
seizure, unconsciousness, and death.
Insulin is used in a wide variety of ways. Most athletes choose to use it immediately
after a workout. Dosages used are usually 1 IU per 10-20 pounds of lean bodyweight.
First-time users should start at a low dosage and gradually work up. For example,
first begin with 2 IU and then increase the dosage by 1 IU every consecutive workout.
This will allow the athlete to safely determine a dosage. Insulin dosages can vary
significantly among athletes and are dependent upon insulin sensitivity and the use
of other drugs. Athletes using growth hormone and thyroid will have higher insulin
requirements, and therefore, will be able to handle higher dosages.
Humilin R should be injected subcutaneously only with a U-100 insulin syringe.
Insulin syringes are available without a prescription in many states. If the athlete
can not purchase the syringes at a pharmacy, he can mail order them or buy them on
the black market. Using a syringe other than a U-100 is dangerous since it will be
difficult to measure out the correct dosage. Subcutaneous insulin injections are usually
given by pinching a fold of skin in the abdomen area. To speed up the effect of the
insulin, many athletes will inject their dose into the thigh or triceps.
Most athletes will bring their insulin with them to the gym. Insulin should be
refrigerated, but it is all right to keep it in a gym bag as long as it is kept away
from excessive heat. Immediately after a workout, the athlete will inject his dosage
of insulin. Within the next fifteen minutes, he should have a carbohydrate drink such
as Ultra Fuel by Twinlab. The athlete should consume at least 10 grams of carbohydrates
for every 1 IU of insulin injected. Most athletes will also take creatine monohydrate
with their carbohydrate drink since the insulin will help to force the creatine into
the muscles. An hour or so after injecting insulin, most athletes will eat a meal
or consume a protein shake. The carbohydrate drink and meal/protein shake are necessary.
Without them, blood sugar levels will drop dangerously low and the athlete will most
likely go into a state of hypoglycemia.
Many athletes will get sleepy after injecting insulin. This may be a symptom of
hypoglycemia, and an athlete should probably consume more carbohydrates. Avoid the
temptation to go to bed since the insulin may take its peak effect during sleep and
significantly drop glucose levels. Being unaware of the warning signs during his slumber,
the athlete is at a high risk of going into a state of severe hypoglycemia without
anyone realizing it. Humulin R usually remains active for only 4 hours with a peak
at about two hours after injecting. An athlete would be wise to stay up for the 4
hours after injecting.
Rather than waiting to the end of a workout, many athletes prefer to inject their
insulin dosage 30 minutes before their training session is over and then consume a
carbohydrate drink immediately following the workout. This will make the insulin more
efficient at bringing glycogen to the muscles, but it will also increase the danger
of hypoglycemia. Some athletes will even inject a few IUs before lifting to improve
their pump. This practice is extremely risky and best left to athletes with experience
using insulin. Finally, some athletes like to inject insulin upon waking in the morning.
After the injection, they will consume a carbohydrate drink and then have breakfast
within the next hour. Some athletes find this application of insulin very beneficial
for putting on mass, while others will tend to put on excess fat using insulin in
Insulin use can not be detected during a drug test. For this reason, along with
the fact that it is cheap and readily available, insulin has become a popular drug
among the competitive athlete. However, before an athlete attempts to use insulin,
he should educate himself and make himself aware of the consequences. One mistake
in dosage or diet can be potentially fatal.
Effective Dose: 1IU per 10-20 lbs. of body weight.
The Physiological Role of Insulin in the Body:
Insulin is a hormone which is manufactured in the pancreas and which has a number
of important physiological actions in the body. It is an essential hormone in maintaining
the body's blood glucose level so that the brain, muscles, heart and other tissues
are adequately supplied with the fuel they require for normal cellular metabolism
and normal function. Insulin also plays an essential role in fat and protein metabolism.
For example, it promotes transport of amino acids from the bloodstream into muscle
and other cells. Within these cells, insulin increases the rate of incorporation of
amino acids into protein (amino acids are the building blocks of protein) and reduces
protein break down in the body ("catabolism"). These physiological actions
probably form the basis of speculation regarding the additional anabolic gains which
might be made through the use of exogenously administered insulin.
Normally, blood glucose and blood insulin levels are not both elevated for any
extended period of time as these two chemicals influence each other through a feedback
system in the body. In the post-absorptive state, the blood insulin concentration
tends to decrease during exercise, allowing the blood glucose to be maintained at
or above resting levels and to provide increased energy supplies (fuel) to muscle
cells. Following a meal, the blood glucose and amino acid levels rise (the absorptive
state) and this triggers an increase in insulin release from the pancreas, driving
glucose and amino acids from the blood into cells and maintaining the blood glucose
level within a certain physiological (operating) range.
Intending users should also be aware that insulin stimulates lipid (fat) synthesis
from carbohydrate ("lipogenesis"), decreases fatty acid release from tissues
("lipolysis") and leads to a net increase in total body lipid stores. The
development of such increased body fat stores runs counter to the training goals of
most body builders, athletes and those seeking to improve their physical appearance.
In striving to become bigger, stronger, more competitive or more physically attractive
you should also remember that no matter what you do, your genetic make-up will have
an influence on what you are able to achieve. It is important to realize that you
cannot look exactly like the role model you admire because you have inherited a different
set of genes.
The Glycemic Index Factor:
Scientists have discovered that carbohydrate containing foods can be measured
and ranked on the basis of the rate and level of blood glucose increase they cause
when eaten. This measurement is called the "Glycemic Index" or "G.I.
factor". The rate at which glucose enters the bloodstream affects the insulin
response to that food and ultimately affects the rate at which this glucose (fuel)
is made available to exercising muscles.
Low G.I. foods are those measuring less than 50 on a scale of 1-100. Moderate
G.I. foods are those with a reading of 50-70 and high G.I. foods are those measuring
71 or greater on this scale. Pure glucose has a G.I. of 100.
Foods which have a high G.I. produce a rapid increase in blood glucose and blood
insulin levels. Examples of such high G.I. foods are potatoes, ice cream, many cereals
particularly those with a high sugar content, some varieties of rice (e.g. Calrose)
Foods with an moderate G.I. include some brands of muesli, some varieties of rice,
white or brown bread, honey and some cereals.
Foods with a low G.I. produce a slower, smaller but more sustained increase in
blood glucose levels. Examples of such low G.I. foods are pasta, varieties of high
amylose rice, barley, instant noodles, oats, heavy grain breads, lentils, and many
fruits such as apples and dried apricots. Low G.I foods are advantageous if consumed
at least two hours before an event. This gives time for this food to be emptied from
the stomach into the small intestine. Since these foods are digested and absorbed
slowly from the gastro-intestinal tract, they continue to provide glucose to muscle
cells for a longer period of time than moderate or high G.I. foods, particularly towards
the end of an event when muscle glycogen stores may be running low. In this way, low
G.I. foods can increase a person's exercise endurance and prolong the time before
exhaustion sets in.
High G.I. foods, preferably in the form of liquid foods or glucose drinks of approximately
6% in concentration, can enhance endurance during a very strenuous event lasting more
than 90 minutes. ("strenuous" being defined as an athlete exercising at
more than 65% of their maximum capacity). Some athletes may prefer food rather than
liquid replenishment. Miller suggests glucose enriched honey sandwiches, which
have a G.I. factor of 75 or jelly beans, which have a G.I. factor of 80.
Miller suggests that an athlete who is engaged in a prolonged strenuous event
should consume between 30 and 60 grams of carbohydrate per hour during the event.
High G.I. foods are also desirable after completing an exhausting sporting or
training event when muscle and liver glycogen stores have been depleted, as they provide
a rapidly absorbed source of glucose and stimulate insulin release from the pancreas.
This insulin in turn stimulates the absorption of glucose into liver and muscle cells
and its storage as hepatic and muscle glycogen, optimizing recovery and preparation
for the next training or competitive event.
It has been shown that greatest benefit can be had if an athlete consumes these
high G.I. carbohydrate foods as soon as possible after an event, preferably within
an hour or less. It is further recommended that a high carbohydrate intake be maintained
during the next 24 hours. Miller suggests eating at least one gram of carbohydrate
per kilogram body weight each 2 hours after prolonged heavy exercise and at least
10 grams of high G.I. carbohydrate per kilogram body weight over the 24 hour period
following this exercise.
For these reasons, an athlete who needs to maintain a high level of activity and
performance on consecutive days or more extended periods of time should eat large
amounts of high G.I. foods. However, a reasonable quantity of low G.I. carbohydrate
food should be consumed before an event in order to improve endurance.
A Natural Method of Maintaining an Elevated Blood Insulin Level:
Noting the hypothesis that an elevated blood insulin level may be of some advantage
to bodybuilders, Fahey and his colleagues (1993) undertook an experiment in which
they fed athletes a liquid meal of "Metabolol", which consisted of 13.0g
protein, 31.9g carbohydrate and 2.6g fat per 100ml and provided 825kJ of energy.
These researchers demonstrated that it is possible with such intermittent feeding
during intense weight training to maintain a person's blood glucose at or above resting
levels and at the same time, significantly increase insulin levels for the duration
of the workout. This suggests a potentially effective and safe non-drug method for
achieving a sustained elevation of blood insulin levels.
The authors of this research commented that "theoretically, this could provide
a biochemical environment conducive to accelerating the rate of muscle hypertrophy
and inhibiting protein degradation". However, the writer knows of no scientific
studies which support this theory.
It is also relevant to note that muscle repair and growth begins in the hours
and days following heavy exercise. It is doubtful that the use of insulin just prior
to a workout will have any anabolic effects over and above natural processes, at this
time. However, use of insulin prior to a workout will certainly expose you to much
greater risk of serious harm. If you believe it is beneficial to have a higher insulin
blood level during workouts, use the natural method outlined here.
Level of Risk Associated with Insulin Use:
The use of all drugs carries some risk along with potential or perceived benefits,
whether used for legitimate medical reasons or for other purposes. Insulin carries
some risk even when used by an insulin dependent diabetic, as demonstrated by the
observation that some diabetics run into difficulties with their treatment from time
to time and often require assistance to restabilize their medical condition and insulin
requirements. If used by a healthy non diabetic person in whom there is no natural
deficiency in insulin production or reduced insulin sensitivity and in the absence
of medical advice and monitoring, the risks may be substantially increased.
The major risk associated with insulin is a physical state known as hypoglycemia
or "low blood sugar". This occurs when the level of glucose in the blood
falls below a certain level required for normal body function. If the blood glucose
level is substantially reduced below this normal level and if this is not quickly
corrected, there is a risk of disorientation, collapse, coma, permanent brain damage
and even death. Exercise and reduced food intake decreases the body's need for insulin
and increases the risk of hypoglycemia associated with non-medical use of insulin.
It is difficult to provide a quantitative estimate of risk for any drug but on
a scale of risk in relation to other non-medical and unsanctioned drug use, the use
of insulin in this manner would rank towards the higher end of the scale. If zero
equals "no risk" of harm to a person's health and ten equals "extreme
risk", the use of anabolic steroids in a non-medical context might rate towards
the middle of the scale of risk (particularly in the medium to long term) whilst insulin
would rate higher. This level of risk associated with insulin use will depend on a
number of factors:
Whether the person is a diabetic or not: non-diabetics and lean healthy people
are more sensitive to the blood glucose lowering effects of insulin than diabetics;
Type of insulin: short acting insulin preparations are considerably safer than
long acting preparations because with short acting types, it is much easier to avoid
hypoglycemia with adequate food intake. With the non-medical use of longer acting
insulin preparations, a person is at real risk of experiencing hypoglycemia late in
the day, particularly in between meals, during or after exercise and when asleep.
Regardless of this advice, some people are in reality using a mixture of short and
long acting insulin preparations and exposing themselves to unnecessary increased
Food intake: the type and timing of food consumed, its glycemic index (the glucose
elevating effect) and the amount consumed;
Timing of insulin administration in relation to food intake and exercise;
Individual variation: two different people can respond in a very different way
to a given dose of insulin, even if they are of a similar height, weight and other
personal characteristics. The fact that a certain dose does not seem to cause a problem
for one person does not mean this will be so for another. In addition, the response
to insulin will also vary greatly within any one individual over time, according to
changes in one or more of the above noted factors.
5-10 Units of a short acting preparation may have little or no observable impact
on someone who eats a meal soon before or after but this dose could cause hypoglycemia
and collapse in a person who has not consumed adequate food in close proximity to
the time when the insulin begins to take effect (insulin starts to take effect within
5-10 minutes if injected by intra-muscular route and in 30-60 minutes if injected
by subcutaneous route). Foods with a high glycemic index will maintain the blood glucose
level for a short period of time, perhaps an hour or so whilst those with a low glycemic
index will provide for more sustained glucose levels. Risk Reduction Advice:
Given the risks of using insulin for non medical purposes, the best advice one
can give is not use it in this way. Even the body building magazines such as "Muscle
Media 2000" advise: "If you're thinking about using insulin, think twice
- it's really risky!"(3) However, if you are not persuaded by this advice and
are determined to pursue its use in the hope of achieving some additional anabolic
or other gains, you should take the following precautions:
Consider using the natural method of raising your blood insulin level during workouts
by consuming glucose containing fluids at intervals during exercise. These fluids
may have a protein sparing effect and at the same time, will help maintain keep your
blood glucose and blood insulin levels. However, if you decide to use insulin, you
should consider the following advice:
Always use insulin in the presence of someone else who knows about and understands
the exact risks of using insulin in this manner, so they are able to act quickly and
appropriately should something go wrong;
Always use a sterile needle and syringe every time and a clean injecting technique
(e.g. don't touch the needle or the skin where you are going to inject, with your
fingers and don't breathe on or cough over the injection site before or after injecting).
Be aware that 1.0 ml of insulin contains one hundred International Units (100 IU),
0.1 ml of insulin contains ten (10) IU and 0.01 ml contains one (1.0) IU. So take
care in measuring out your insulin ….it is very concentrated!
Note that 0.01 ml is the volume contained in the space between the smallest graduated
markings on a 1.0 ml Terumo diabetic syringe;
Inject by the subcutaneous route (injecting just under the skin and preferably
in the abdominal area or outer part of the upper thigh), not intramuscularly or intravenously
as using the latter routes can lead to a rapid rise in blood insulin level and a sudden
Alternate your injection sites in order to minimize tissue damage ("lipoatrophy"
Always use a short acting, "regular" insulin (e.g. Actrapid, Insulin
Neutral, Humulin R, Hypurin Neutral) rather than a longer acting insulin preparation
(e.g. Semilente, Lente or Ultralente);
Use a human insulin rather than an animal insulin preparation if possible (there
is little animal insulin available now);
Start with no more than 5 IU (0.05 ml) of this short acting/ regular insulin preparation
and increase the dose gradually over a period of one week, to a dose no higher than
20 IU (0.20 ml) per day. Doses above this will expose you to progressively greater
risk and most body builders who use insulin believe there is no advantage in taking
doses higher than this. Anecdotal evidence amongst bodybuilders suggests increased
doses leads to excess bodyfat accumulation.
The writer would caution against users falling into the trap of thinking: "If
20 units is good, 40 units will be twice as good" or "Joe says he injected
20 units and it didn't affect him, so it will be safe for me to inject 30 or 40 units".
All drugs have a therapeutic dose range and above this, may be toxic or even lethal.
If you are not diabetic, your body does not require additional insulin and there is
no therapeutic range for you. In addition, people are different and often respond
differently to drugs. An individual may also respond differently to the same drug
in the same dose at different times, depending on a wide range of factors such as
their general health, alcohol or other drugs taken, food eaten, exercise undertaken
before, during or after drug administration and so on.
Don't use a medium or long acting insulin in the middle or latter part of the
day, as you may very well experience a hypoglycemic attack whilst you are asleep.
If this happens, neither you nor anyone else will be aware of or able to respond to
your urgent need for glucose, in order to prevent possible serious harm.
Close attention to diet is extremely important in people using insulin, whether this
is for legitimate medical purposes or for other reasons. You can reduce your risk
by consuming an adequate amount and mixture of high and low G.I. carbohydrate foods
and drinks immediately after using insulin and at regular intervals (every 2-3 hours) throughout the day.
High G.I. carbohydrates (e.g. sweets, soft drinks and ice-cream) will raise your
blood sugar quickly and prevent early hypoglycemia. Low G.I. carbohydrates (e.g. white
pasta, high amylose rice, softened whole grain breads and instant noodles) are metabolized
more slowly and will keep your blood glucose level up over a more extended period
of time, when the medium acting insulin preparations begin to take effect;
55-65% of your total daily energy intake should be in the form of carbohydrates,
15-20% as protein and ~20% as fat. You should seek advice from a dietitian about your
daily requirements but most heavy training athletes need to consume between 3,000
and 5,500 Calories per day (depending on the sport and level of training) and between
450 and 800 grams of carbohydrate each day. If you are a body builder who weighs 100
kg and your total energy requirements are calculated to be 4,000 calories/ day, you
should aim to eat approximately 570 grams of carbohydrate each day. If your total
energy requirements are calculated to be 5,000 calories/ day, you should aim to eat
approximately 720 grams of carbohydrate each day.
Divide up your calculated total daily carbohydrate requirements over the course
of your waking hours and consume frequent carbohydrate meals throughout the day. For
example, if you require 4,000 calories per day, you might eat six meals of 650-700
Calories at 2-3 hour intervals.
This would mean eating approximately 90-100 grams of carbohydrate each meal, which
for example you will obtain from 7 slices of bread alone or 4-5 slices of bread with
1 ? tablespoons of honey or 500 ml of Sustagen or 3 slices of bread eaten with a 450
gram can of baked beans. You can refer to the attached food tables to work out your
own requirements according to your own food preferences. You will need to choose a
mixture foods from this table with a high, medium or low G.I., according to the nature
and level of the training you are doing.
Once again, the writer would strongly recommend that you consult a dietitian who
has an interest and experience in sports nutrition, in order to assist you design
a dietary program which is best suited to your training goals and needs and to your
food preferences. It is equally important that you find a dietitian with whom you
feel comfortable telling about your insulin or other performance enhancing substance
use, as their advice may otherwise be less than useful to you. If your dietitian does
not know about and does not take such substance use into account, their advice may
even add to the dangers associated with this substance use.
Always have a source of glucose or other high G.I. food ready at hand, in case
you should begin to experience the symptoms of hypoglycemia. If this does occur, you
should take this glucose or food without delay. You should eat or drink 15-20 grams
of carbohydrate to begin with, which is contained in ~ 2 slices of white or brown
bread, two glasses of milk, a half glass of soft drink, a tablespoon of honey or six
Other examples of glucose or other high Glycemic index carbohydrate preparations
which you can use include: glucose tablets, glucose powder mixed in a small volume
of water, barley sugar, or other sweets or if these are not immediately available,
a sugar containing cordial, soft drink or plain sugar dissolved in water. This should
be followed by an adequate low Glycemic index carbohydrate meal to prevent further
hypoglycemia since the insulin levels are likely to remain high for some hours after
the high Glycemic index carbohydrates are used up (metabolized) in the body.
The Crucial Role of the Friend or Peer Observer:
If you are going to use insulin, it is essential that you have a friend or peer observer
remain with you in case you experience problems. This person really needs to be with
you for the whole time while the insulin preparation used is working.
Be aware that the risk of hypoglycemia occurs not at the time of insulin injection
but rather, when the insulin starts to take effect. The risk will be greatest when
your insulin blood level nears or reaches its highest level, usually 30-60 minutes
afterwards if a short acting insulin preparation is used (by subcutaneous injection)
and up to 20 hours later if a long acting insulin is used.
Consider giving this paper to the person who is going to be with you when you
use insulin, so they are aware of the things to look out for and what to do if you
should experience a hypoglycemic reaction. The following instructions are for a peer
observer or other person who may find you experiencing difficulty as a result of overdosing
on insulin or any other drug or combination of drugs.
Instructions for the Peer Observer Assisting an Insulin User.
If the person who has used insulin states that they are beginning to feel any of
the following symptoms: faintness, dizziness, thirst, hunger, nausea, weakness, sweating.
Or if you observe that they have become: confused, disorientated, sweaty, drowsy.
You should immediately give them glucose or a sugar containing drink or food as
mentioned above. However, you should not try to give a person food or fluids if they
are so drowsy that they are unable to swallow it, since they will be at risk of accidentally
breathing in (aspirating) this food or fluid. If they cannot readily respond to your
questions or your commands, you should assume they are unable to swallow anything
If the person loses consciousness, you should place them in either a "lateral"
or "coma" position, tilting the head fully back and jaw forward, in order
to ensure an open airway and protect them from possible aspiration. Keep them in this
position while medical assistance is being sought.
You should then immediately call an ambulance by dialing "911", to get
them to a hospital without any delay whatsoever. When the ambulance arrives, you should
tell the ambulance officers exactly what the person has taken and what you have observed
so the correct treatment can be provided promptly. This is essential as the person's
life may be at stake.
Severe hypoglycemia or a combination of alcohol and other drugs, particularly
drugs which suppress the central nervous system, can cause a person to stop breathing
and their heart to stop beating. Remember, it only takes a few minutes for someone
to suffer permanent brain damage or to die, once they stop breathing.
There are several common signs which may be apparent in someone who has overdosed
from one or a combination of drugs.
very slow or shallow breathing or no breathing at all (listen close to the person's
mouth and nose for breath sounds and look for movement of their chest wall) snoring
or gurgling breathing in someone who is asleep blue lips and fingernails (caused by
lack of oxygen) no response to shaking, calling their name or pain (try pinching their
earlobe and pressing down hard on one of their fingernails with a pen) very slow,
faint pulse or no pulse at all.
What To Do in the Event of an Overdose:
stay calm, squeeze earlobe/ press on fingernail of person in an effort to arouse
them if person responds, try to walk them around if no response, check person's breathing
and pulse if unconscious but breathing, place in lateral or coma position call an
ambulance by dialing 911.
They will give you advice on what to do, which might include:
if there is a pulse but the person is not breathing, start artificial respiration,
otherwise known as Expired Airways Resuscitation (EAR), without delay if no pulse,
start cardio-pulmonary resuscitation (CPR) stay with the person, continuing to administer
artificial respiration or CPR until the ambulance arrives. Keep them in the lateral
or coma position if they are breathing on their own. tell the ambulance officers exactly
what they may have taken and what you have observed.
The writer would like to emphasize once more that this paper should in no way
be construed as an encouragement to people to use insulin in an effort to increase
muscle mass, sports performance or appearance. Rather, it represents a pragmatic attempt
at providing harm reduction advice to people who choose to take the risk of using
insulin in this way, despite their knowledge of those risks.