Testosterone Cypionate is a single-ester, insulin pumps long-acting form of testosterone. Due to the length of its ester (8 carbons) it is stored mostly in the adipose insulin pumps tissue upon intra-muscular injection, and then slowly but very steadily released over a certain period of time. A peak is noted after 24-48 hours insulin pumps of injection and then a slow decline, reaching a steady point after 12 days and staying there over 3 weeks time. A long-acting testosterone insulin pumps ester may be the best for all your mass-building needs, but it's not an easy product to use. Nolvadex and Proviron will come in very handy in such
cases and post-cycle. HCG and Clomid or Nolvadex will be required as well to help restore natural testosterone.Frequency of side effects insulin pumps is probably highest with this type of product.
CytomelÂ® (liothyronine sodium)
Diazepam should not be administered insulin pumps parenterally to patients with acute ethanol intoxication, shock, or coma because the drug can worsen insulin pumps CNS depression.
by Bill Roberts - Unlike most oral steroids, which are Class II steroids giving most of their anabolic insulin pumps effect by means other than the androgen receptor (AR), it seems that oxandrolone probably does have good binding to the AR, and is therefore a Class I steroid,
while having little other effect. By itself it is considered to be a weak anabolic.
It tells us many things. Let's start with what we want, insulin pumps then see where that leads us. What do we want? Bigger muscles. More muscle cells that we will later insulin pumps grow with exercise and gear. A pump? Fatloss? Yeah, right. You can get a pump with a good "pump" product for a quarter of the price of IGF-1. insulin pumps Fatloss? Clen/Alb and T3/T4 will give it to you again at a fraction of the price of IGF-1. More muscle cells, you can ONLY get with IGF-1 (and MGF too). Nothing else will give it to you and if you are using IGF-1 for anything
else, you are misusing it. More muscle cells is CLEARLY the best use for IGF-1.
Side effects of Testosterone enanthate
Normally, blood glucose and blood insulin levels are not both elevated for any extended period of time as these two chemicals influence insulin pumps each other through a feedback system in the body. In the post-absorptive state, the insulin pumps blood insulin concentration tends to decrease during exercise, allowing the blood glucose to be maintained at or above resting levels insulin pumps and to provide increased energy supplies (fuel) to muscle cells. Following a meal, the blood glucose and amino acid levels rise (the
absorptive state) and this triggers an increase in insulin release from the pancreas, driving glucose and amino acids from the insulin pumps blood into cells and maintaining the blood glucose level within a certain physiological (operating) range.
Recreational users might insulin pumps also be interested in Masteron. Although dihydrotestosterone is not highly active in muscle tissue, the 2 alkylation insulin pumps present on drostanoione considerably intensifies its anabolic effect. It can therefore be used somewhat effectively as bulking agent, insulin pumps providing a consistent gain of high quality muscle mass. It can also be successfully combined with other
steroids for an enhanced effect. Mixing drostanoione with an injectable anabolic such as insulin pumps Deca-DurabolinÂ® (nandroione decanoate) or EquipoiseÂ® (boldenone undecylenate) can prove quite useful for example, the two providing notably enhanced insulin pumps muscle gain without excessive water retention. For greater mass gains, one can alternately addition a stronger androgen such as Dianabol or an insulin pumps injectable testosterone. The result here can be an extreme muscle gain, with a lower level of water retention & other estrogenic side effects than if these steroids were used alone (usually in higher doses). Masteron could of course be used during
cutting phases of training as well. A cycle of this drug combined with WinstrolÂ®, PrimobolanÂ® or Cxandrolone should provide great muscle retention insulin pumps and fat loss, during a period which can be very catabolic without steroids. It is an added benefit that none of these steroids aromatize, and therefore insulin pumps there is no additional worry of unwanted water/fat retention.
Safety for use in pregnancy and lactation has not been insulin pumps established.
An effective daily dose for athletes is 15-40 mg/day. Steroid novices do not need more than 15-20 mg./day which is sufficient to achieve exceptional results over a period of
Effective Dose (Women): Not recommended
The history of insulin pumps Cialis cannot be discussed without mentioning Pfizer's drug, Viagra. The FDA's approval on March 27, 1998, led this prescription drug, Viagra, to a insulin pumps ground breaking success in just the first year of introduction as Pfizer sold drugs worth insulin pumps over a billion dollars. However, things changed considerably for the giant of erectile dysfunction insulin pumps drugs when the FDA also approved Levitra on August 19, 2003, and Cialis on November 21, insulin pumps 2003. In 1993 the drug company Icos began studying IC351, which is a PDE5 enzyme inhibitor, and this is basically
the process through which the erectile dysfunction drugs work. In 1994, Pfizer scientists discovered that sildenafil insulin pumps citrate, which is a white crystalline powder that temporarily normalizes erectile function insulin pumps of the penis by blocking an enzyme known to inhibit the production of a chemical that causes insulin pumps erections, caused the heart patients that were participating in a clinical study of a heart medicine to have erections. insulin pumps Although the scientists were not testing the chemical compound IC351 for erectile dysfunction, the compound seemed to have a side effect which could potentially be worth millions, if not billions of dollars.
Soon Icos received its very first patent in 1994 on IC351, and the clinical trials of phase 1 took place insulin pumps in 1995. In 1997, phase 2 clinical studies began and Icos performed its first study on patients with erectile dysfunction. insulin pumps Phase 2 lasted about two years, and after that phase 3 began.
HCG was at one point looked at to see if it could cany the AIDS virus, due to insulin pumps the fact that it is biologically active, but the latest word is that this could not be possible in any way. HCG must be refrigerated after it is mixed together and it then has a life of about 10 weeks. It is taken intramuscularly only. This drug is
often available by order of a physician if you show symptoms of hypogonadism.
Medications similar to testosterone that are taken by mouth for a long time may cause serious damage to the liver or liver insulin pumps cancer. Testosterone gel has not been shown to cause this damage. Testosterone may increase the risk of developing prostate insulin pumps cancer. Talk to your doctor about the risks of taking this medication. Testosterone gel may cause other side effects. Call your doctor insulin pumps if you have any unusual problems while taking this medication.
Half-life means nothing. Localized vs systemic = bad argument. You want localized
effects. Period. You get them by pinning immediately postworkout. Period. End of argument.
This steroid works well for the insulin pumps promotion of strength and duality muscle mass gains, although it's mild nature makes it less than ideal for bulking purposes. Among bodybuilders it insulin pumps is most commonly used during cutting phases of training when water retention is a concern. The standard dosage for men insulin pumps is in the range of 20-50mg per day, a level that should produce noticeable results. It can insulin pumps be further combined with anabolics like Primobolan and Winstrol to elicit a harder, more defined look without added water retention. Such
combinations are very popular and can dramatically enhance the show physique. One can also add strong non-aromatizing insulin pumps androgens like Halotestin, Proviron or trenbolone. In this case the androgen really helps to harden up the muscles, while insulin pumps at the same time making conditions more favorable for fat reduction. Some athletes do choose to incorporate oxandrolone into bulking insulin pumps stacks, but usually with standard bulking drugs like testosterone or Dianabol. The usual goal in this instance insulin pumps is an additional gain of strength, as well as more quality look to the androgen bulk. Women who fear the masculinizing effects of many steroids
would be quite comfortable using this drug, as this is very rarely seen with low doses. Here a daily insulin pumps dosage of 5mg should illicit considerable growth without the noticeable androgenic side effects of other drugs. Eager females may wish to addition insulin pumps mild anabolics like Winstrol, Primobolan or Durabolin. When combined with such anabolics, the user should notice faster, more pronounced muscle-building insulin pumps effects, but may also increase the likelihood of androgenic buildup.
Testosterone used alone is capable of giving very effective results, particularly with doses over one gram per week, and can give substantial results
with only 500 mg/week. If no other drugs are used, however, side effects such as gynecomastia are fairly insulin pumps likely. Prostate enlargement, worsening of acne, and acceleration of male pattern baldness (for those genetically susceptible to it) are particularly insulin pumps severe because of the effectively-higher androgen levels seen in these tissues as a result of local conversion insulin pumps to the more-potent DHT. Synthetics which do not convert to DHT give only the same effective level of androgen in these tissues as in the body as a whole, rather than effectively three times the level. This is a significant advantage.
High Blood Pressure:
An allergic reaction to this medicine is unlikely, but seek immediate insulin pumps medical attention if it occurs. Symptoms of an allergic reaction include rash, itching, unusual swelling, severe dizziness, or trouble breathing. insulin pumps
Excessive water retention and aromatizing can be avoided in most cases by simultaneously taking Nolvadex and Proviron.
Liver Toxic: No
Popular steroids stacked with Masteron(Masteron 100) (drostanolone propionate) include Parabolan (trenbolone insulin pumps hexahydrobencylcarbonate), Winstrol (stanozolol), and Anavar (oxandrolone). Athletes rarely experience any side effects.
It is not hepatoxic, and gynecomastia should not be a concern since it does not convert into estrogen. Some possible insulin pumps side effects of Masteron(Masteron 100) include acne, accelerated hair loss, and increased aggression. insulin pumps The main disadvantage is a very poor availability on the black market and its high price.
VIAGRA Is insulin pumps Not for Everyone:
Nitrates are also found in recreational drugs such as amyl nitrate or nitrite insulin pumps ("poppers"). If you are not sure if any of your medications contain nitrates, or if you do not understand what nitrates are, ask your healthcare provider or pharmacist.
Day 5: 100 mcg
T-Prop. Disp. 10, 20 mg/ml; Disperga A
EPO can be given intra-muscular or intravenously, insulin pumps of course with intravenously it will take effect much faster. With a half-life of 4 to 5 hours long, and insulin pumps when administered intra-muscular half-life will be 12 to 18 hours. So when used medically the dosage insulin pumps is 15-50IU/kg of body weight, given three times a week.
Epilepsy or history of seizures insulin pumps — Although some benzodiazepines are used in treating epilepsy, starting or suddenly stopping treatment with these medicines may increase seizures
Steroid novices should not
(yet) use Trenabol Depot. The same is true for women; however, there are enough female athletes who do not care since the female organism reacts insulin pumps to the androgenic charge and the strong anabolic effect of Trenabol Depot with distinct gains insulin pumps in muscles and strength, especially from a female point of view. Thus the entire body has a harder and more athletic look. insulin pumps Trenabol Depot without a doubt is an enticing product for ambitious female athletes. In the end insulin pumps everything depends on your personal willingness to take risks, ladies. The fact is that the standards on the national and international competition scenes in female bodybuilding
have achieved levels which cannot be reached without the administration of strongly insulin pumps androgenic steroid compounds. A combination well liked by female bodybuilders consists of 76 mg Trenabol Depot/week, 20 mg Winstrol tablets/day, and insulin pumps 100 mcg Clenbuterol/day Women who do not in-ject more than one ampule of Trenabol Depot per week and insulin pumps who limit the period of intake to 4-5 weeks can mostly avoid or minimize virilization symptoms. insulin pumps Female athletes who are overdoing it or who are sensitive to the androgenic part of trenbolone hexahydrobencylcarbonate insulin pumps can be confronted with some unpleas-ant surprises after several weeks
of use: acne, androgenically caused hair loss on the scalp, irregular menstrual cycles, missed periods, much insulin pumps higher libido, aggressiveness, deep voice, chtorial hypertrophy, and increased hair growth on face and on the legs. The last three side effects are insulin pumps mostly irreversible changes.
Because Phentermine may cause drowsiness, it is recommended insulin pumps that you take your dose early in the day. The best time is 30-60 minutes before breakfast, insulin pumps while your stomach is empty. Take the tablet in one piece, or, at most, it may be broken in two. Do not chew the tablet or crush it into a powder.
You may get drowsy or
dizzy. Do not drive, use machinery, or do anything that needs mental alertness until insulin pumps you know how diazepam affects you. To reduce the risk of dizzy and fainting spells, do not stand or sit up insulin pumps quickly, especially if you are an older patient. Alcohol may increase dizziness and drowsiness. Avoid alcoholic drinks.
Andriol is actually contained in a natural ester base, one, which is very easy on the body. This insulin pumps product's advantageous properties are similar to other testosterones in that it promotes rapid strength and weight gains. It, like other testosterones, promotes the storage
of glycogen as well as ATP. Andriol does not seem to exhibit the degree of LH and FSH insulin pumps suppression that is seen with other testosterones and androgens.
Alternative names: Aquaviron Testosterone Suspension
Acne: Yes, insulin pumps especially in higher dosages
The growth hormones is a polypeptide hormone consisting of insulin pumps 191 amino acids. In humans it is produced in the hypophysis and released if there insulin pumps are the right stimuli (e.g. training, sleep, stress, low blood sugar level). It is now important insulin pumps to understand that the freed HGH (human growth hormones) itself has no direct effect but only stimulates the
liver to produce and release insulin-like growth factors and somatomedins. These growth factors insulin pumps are then the ones that cause various effects on the body.
Common dosage of clenbuterol is 5-7 tablets, 100-140 mcg per day. For women insulin pumps 80-100 mcg/day are usually sufficient. It is important to begin by taking only one tablet on the first day and then increasing insulin pumps the dosage by one tablet each of the following days until the desired maximum dosage is reached.
Chem. Abstr. Name: 17beta-Hydroxyestra-4,9,11-trien-3-one (Trenbolone Base + Acetate
No. With KAMAGRA, you must be sexually aroused to get an erection. If you take insulin pumps KAMAGRA and are not sexually stimulated, nothing will happen–you won't get an erection insulin pumps just by taking the pill. KAMAGRA is not a hormone. It is not an aphrodisiac. It's a prescription medication that can improve the erectile insulin pumps function of most men with erection problems.
Nolvadex C&K (Tamoxifen) blocks insulin pumps the effects of the estrogen hormone in the body. Nolvadex C&K is used to treat breast cancer in women or men but tamoxifen may also be used to treat other kinds of cancer, as determined by your doctor.
Testosterone is a powerful hormone with notably prominent side effects. Much of which stem from the fact insulin pumps that testosterone exhibits a high tendency to convert into estrogen. Related side effects may therefore become a problem during a Testosterone Enanthate insulin pumps cycle. For starters, water retention can become quite noticeable. This can produce a clear loss of muscle definition, insulin pumps as subcutaneous fluids begin to build. The storage of excess body fat may further reduce the visibility of muscle features, another insulin pumps common problem with aromatizing steroids. The excess estrogen level during/after your cycle also
has the potential to lead up to gynecomastia. Adding an ancillary drug like Nolvadex insulin pumps and/or Proviron is therefore advisable to those with a known sensitivity to this side effect. As discussed insulin pumps throughout this book, the antiaromatase Arimidex is a much better choice. It is believed that the use of an antiestrogen insulin pumps can slightly lower the anabolic effect of most androgen cycles (estrogen and water weight are often thought to facilitate insulin pumps strength and muscle gain), so one might want to see if such drugs are actually necessary before committing to use. A little puffiness under the nipple is a sign that gynecomastia is developing.
If this is left to further develop into pronounced swelling, soreness and the growth of small lumps under the nipples, some form insulin pumps of action on should be taken immediately to treat it (obviously quitting the drug or adding ancillaries). insulin pumps
Efficacy in bitemporal recession has not been established.
Anabolic steroids promote the growth insulin pumps of skeletal muscle and the development of male sexual characteristics but do also have some insulin pumps other effects.
Finasteride that is a specific inhibitor of 5a-reductase. Harifin is the enzyme responsible for converting testosterone into DHT (dihydrotestosterone). Harifin
can efficiently reduce the serum concentration of DHT, therefore Harifin minimizes the unwanted androgenic insulin pumps effects that result from its presence. Propecia is the same drug but the tablet contains only 115 of the Harifin dosage. Scientists insulin pumps have long believed that DHT was the main culprit in many cases of male hair loss (along with genetic factors), so there was little insulin pumps doubt after the release of Harifin that Finasteride would eventually be used for this insulin pumps purpose.
You should then immediately call an ambulance by dialing "911", to get them to a hospital without any delay whatsoever. When the ambulance
arrives, you should tell the ambulance officers exactly what the person has taken and insulin pumps what you have observed so the correct treatment can be provided promptly. This is essential as the person's life may be at stake.
HGH insulin pumps itself does carry with it some of its own risks. The most predominantly discussed side effect would be acromegaly, or a noticeable insulin pumps thickening of the bones (notably the feet, forehead, hands, jaw and elbows). The drug can also enlarge vital organs insulin pumps such as the heart and kidney, and has been linked to hypoglycemia and diabetes (presumably due to its ability to induce insulin resistance). Theoretically,
overuse of this hormone can bring about a number of conditions, some life threatening. Such problems however are extremely rare. insulin pumps Among the many athletes using growth hormone, we have very few documented cases of insulin pumps a serious problem developing. When used periodically at a moderate dosage, the athlete should have little cause for worry. Of insulin pumps course if there are any noticeable changes in bone structure, skin texture or normal health and well being during use, HGH therapy should insulin pumps be completely halted.
Usage: Average dose is 100-300 mg per week.
- If you are pregnant or there is possibility to be.
Deca durabolin (Organon): Generic Name - Nandrolone Decanoate
Methenolone comes in orals and injectables. The injectables are to be preferred insulin pumps as they can be used for quite some time and only require injecting once a week. The orals are taking every day, or multiple times a insulin pumps day. An oral passes through the liver twice. An injectable only once. The injectable is more insulin pumps effective since less is broken down.
Before the use of clenbuterol, consult a physician if you have heart or thyroid diseases, high blood pressure, diabetes, glaucoma, difficulty in urination due to an
enlargement of the prostate gland or if you are taking any prescription drugs. Do not use clenbuterol if you are insulin pumps currently taking or have recently taken MAO inhibitor drugs.
Bodybuilders and powerlifters, in particutar, like Oxandrolone for three reasons. First, insulin pumps Oxandrolone causes a strong strength gain by stimulating the phosphocreatine synthesis insulin pumps in the muscle cell without depositing liquid (water) in the joints and the muscles. Powerlifters and weightlifters who do not want to end up in a higher weight class take advantage of this since it allows them
to get stronger without gaining body weight at the same time. The combination of Oxandrolone and 20-30 mg insulin pumps Holotestin daily has proven to be very effective since the muscles also look harder. Similarly good results can insulin pumps be achieved by a simultaneous intake of Oxandrolone and 120-140 mcg Clenbuterol per day. Although Oxandrolone itself does not cause a noticeable insulin pumps muscle growth it can clearly improve the muscle-developing effect of many steroids. Deca Durabolin, Dianabol (D-bol), and the various insulin pumps testosterone compounds, in particular, combine well with Oxandrolone to achieve a "mass buildup" because the strength gain caused by
the intake of these highly tissue-developing and liquid-retaining substances results in an additional muscle mass. A stack insulin pumps of 200 mg Deca Durabolin/week, 500 mg Testoviron Depot (e.g. Testoviron Ethanate 250)/week, and 25 mg Oxandrolone/day leads to a good gain in strength insulin pumps and mass in most athletes. Deca Durabolin has a distinct anabolic effect and stimulates the synthesis insulin pumps of protein; Oxandrolone improves the strength by a higher phosphocreatine synthesis; and Testoviron Depot inereases insulin pumps the aggressiveness for the workout and accelerates regeneration.
Keep Nolvadex in a tightly closed container and out of reach
of children. Store Nolvadex at room temperature and away from excess heat and moisture insulin pumps (not in the bathroom).
Individual results may vary. In clinical trials, CIALIS was shown to improve, up to 36 hours after dosing, the ability insulin pumps of men with ED to have a single successful intercourse attempt. CIALIS has not been studied insulin pumps for multiple sexual attempts per dose.
stay calm, squeeze earlobe/ press on fingernail of person in an effort insulin pumps to arouse them if person responds, try to walk them around if no response, check person's breathing and pulse if unconscious but breathing, place in lateral or coma position
call an ambulance by dialing 911.
The increased aggressiveness is caused by the resulting high level of insulin pumps androgen and occurs mostly when large quantities of testosterone are injected simultaneously insulin pumps with the use of anadrol.
Cialis ® is a treatment insulin pumps for men with erectile dysfunction. This is when a man cannot get, or keep a hard, erect penis suitable for sexual insulin pumps activity.
In case of chest pain occurring during or after sexual activity you should NOT insulin pumps use nitrates but you should seek immediate medical assistance.
Propecia is indicated for the treatment of male
pattern hair loss (androgenetic alopecia) in adult men only.
Tprop. Eifelfango insulin pumps 50 mg/ml; Eifelfango G
Glaucoma, open angle — Benzodiazepines can be used but your doctor insulin pumps should be monitoring your condition carefully.
Anabolic steroids are not recommended during pregnancy. They may cause insulin pumps the development of male features in the female fetus and premature growth and development of male features in the male fetus. Be sure insulin pumps you have discussed this with your doctor.
Thus, Bonavar may even be ideal for use in bridges between cycles (at very low doses under 10mgs perhaps), or as
previously mentioned, for cutting/strength cycles at 50-100mgs.
® is the Novo Nordisk A/S registered trademark for somatropin, a polypeptide hormone of recombinant DNA origin.
Phentermine diet pills are used for a short-term to help you quickly lose weight and fight insulin pumps obesity. You need to develop better eating habits and exercise while taking Phentermine or any other insulin pumps weight loss medication. Diet pills are not a substitute for proper eating or exercise if you want the best results combine Phentermine insulin pumps with your diet plan. Do not share this medication with friends or family.
Clenbuterol is attractive for its pronounced thermogenic effects as well as mild anabolic
5-10 Units of a short acting preparation may have little or no observable impact on someone who eats a meal soon before insulin pumps or after but this dose could cause hypoglycemia and collapse in a person who has not consumed adequate food in close proximity insulin pumps to the time when the insulin begins to take effect (insulin starts to take effect within 5-10 minutes if injected by intra-muscular insulin pumps route and in 30-60 minutes if injected by subcutaneous route). Foods with a high glycemic index will maintain the blood glucose level for a short period of time, perhaps an hour or so whilst those with a low glycemic index will
provide for more sustained glucose levels. Risk Reduction Advice:
Sustanon is a fairly safe steroid but it is probably wise to use insulin pumps an antiestrogen such as Nolvadex (tamoxifen citrate) or Proviron (mesterolone). Athletes interested in rapid size and strength gains find that Sustanon insulin pumps stacks extremely well with orals such as Anadrol (oxymetholone) and Dianabol (methandrostenlone). insulin pumps On the other hand, Sustanon also stacks well with Parabolan (trenbolone hexahydrobencylcarbonate), Masteron (drostanolone propionate), and Winstrol (stanozolol) for athletes seeking the hard, ripped look.
It is easy on the liver
and promotes good size and strength gains while reducing body fat. Deca can be used by almost all insulin pumps athletes, with positive results and very few side effects, deca has gained a reputation as being somewhat of an alleviator of sore insulin pumps joints and tendons. Athletes report that sore shoulders, knees and/or elbows are somehow without pain on insulin pumps the Deca cycle. This drug dramatically improves nitrogen retention and recuperation time between workouts.
The injectable version often gives more results. In similar doses there is still more breakdown upon first pass in the liver, making it difficult to get an equal amount absorbed.
And on top of that it has to be mentioned that most people simply don't take an equal amount. Too many pills, lesser availability, higher insulin pumps cost. Many factors play a role in that. But of course an oral is to be preferred over daily injections insulin pumps as that gives the necessary complications as well. Think of abscesses and lumps, the searching for new injection sites due insulin pumps to pain and so on. Some have solved this problem by simply drinking the Winny injections. It's the insulin pumps same substance, also methylated to withstand the liver, the availability and price are better and its contained in water. So there really aren't many objections
Cialis ® contains lactose and should not be taken by patients with rare hereditary problems of galactose intolerance, insulin pumps the Lapp lactase deficiency or glucose-galactose malabsorption.
Stronger insulin pumps bones
Tablets are green square tablets, with "50" imprinted on one side and "BD" separated by a score line, they can be broken insulin pumps into 2 pieces, and are sealed in foil pouches of 100 tablets.
For those worried about androgenic side-effects (hair insulin pumps loss, prostate hypertrophy, deepening of voice), one can utilize the hair loss treatment finasteride. This blocks the 5-alpha-reductase
enzyme and stops the conversion of testosterone to the more androgenic compound DHT. I'm not a big fan of insulin pumps this, because DHT reduces estrogenic bloat, increases free levels of testosterone and is a very insulin pumps potent androgen that is 3-4 times stronger than testosterone. Those worried about hair loss however, may want to opt for arimidex as insulin pumps their anti-aromatase, since Proviron is a form of DHT after all.
Take this medicine by mouth as needed between four hours and one-half hour before sexual activity (about 1 hour before is most effective); or take as directed by your doctor. Do not take this medicine more often than
once daily as needed. A high fat meal may delay the time of onset of this medicine.
Testosterone is the prime male androgen in the body, and as such still the best possible mass builder in the world. It insulin pumps has a high risk of side-effects because it readily converts to a more androgenic form (DHT) in androgen responsive tissues insulin pumps and forms estrogen quite easily. But these characteristics also provide it with its extreme insulin pumps anabolic tendencies. On the one hand estrogen increases growth hormone output, glucose utilization, improves immunity and upgrades the androgen receptor, while on the other hand a testosterone/DHT
combination is extremely potent at activating the androgen receptor and eliciting major strength and size gains. insulin pumps While not always the most visually appealing result, there is no steroid on earth that packs insulin pumps on mass like testosterone does.
Although the mechanisms underlying age associated muscle loss are insulin pumps not entirely understood, researchers attempted to moderate the loss by increasing the regenerative capacity insulin pumps of muscle. This involved the injection of a recombinant adeno-associated virus directing overexpression of insulin-like growth insulin pumps factor I (IGF-I) in differentiated muscle fibers.
If you have kidney
disease, liver disease, glaucoma, gallstones, epilepsy (or any other seizure disorder), history of stroke, heart problems, or insulin pumps high blood pressure talk to your doctor. You may not be able to take Reductil or you may insulin pumps require a dosage adjustment. Also, DO NOT take Reductil without first consulting with your doctor if you are pregnant or nursing. insulin pumps
CKD's - These are extremely impractical while on a cyclical ketogenic diet (CKD), and are especially dangerous. This brings insulin pumps up blood glucose considerations; it is important to try to maintain relatively stable, or at least not severely depressed, blood glucose
levels. If this guideline is not followed, the user may experience blurred vision and/or extreme fatigue possibly augmented insulin pumps by fainting or lightheadedness.
Stanozolol comes in 50 mg/cc, 2 mg/tab or 5mg/tab. Winstrol Depot is manufactured insulin pumps by Winthrop in USA and by Zambon in Europe. Winstrol depot is very popular anabolic steroid and is a derivative of DHT. It is a relatively low insulin pumps androgenic steroid which does not seem to aromatize. It can be toxic to the liver in excessive dosages. Very few user report water retention or any other side effects. It is a popular all purpose steroid; many stack with Primobolan
depot for cutting, others stack it with testosterone for size and strength gains. Women often use winstrol depot but occasionally insulin pumps it can cause virilization, even at low dosages. Users report that the muscle gains they make are solid, they are well insulin pumps retained after the drug use is discontinued.
if you are taking any form of organic insulin pumps nitrate or nitric oxide donors such as amyl nitrite. This is a group of Medicines ("Nitrates") insulin pumps used in the treatment of angina pectoris ("Chest pain"). Cialis ® has been shown to increase the effects of these drugs. If you are taking any form of nitrate
or are unsure tell you doctor.
Proviron (Mesterolone), an anabolic steroid, is particularly insulin pumps interesting. I suspect that it not only acts as an antiaromatase but in an unknown DHT-like anti-estrogenic manner. This might involve estrogen receptor insulin pumps downregulation for example. In any case, aromatase inhibition and/or Clomid donâ€™t seem to give the same effect on appearance and insulin pumps muscle hardness as when Proviron is included.
The Physiological Role of Insulin in the Body:
Cytomel is not an anabolic/androgenic steroid but a thyroid hor?Âmone. As a substance it contains synthetically manufactured
liothyronine sodium which resembles the natural thyroid hormone tricodide-thyronine insulin pumps (L-T3). The thyroid of a healthy person usually produces two hormones, the better insulin pumps known L-thyroxine (L-T4) and the aforementioned L-trilodine~thyronine (L-T3). Since insulin pumps Cytomel is the synthetic equivalent of the latter hormone, it causes the same processes insulin pumps in the body as if the thyroid were to produce more of the hormone. It is interesting to note that L-T3 is clearly the stronger insulin pumps and more effective of these two hormones. This makes Cytomel more effective than the commercially available L-T4 compounds such as L-thyroxine or Synthroid. The manufacturer
of the German L-T3 compound, Hoechst AG, ascribes the following characteristics to its Thybon drug, making it clear that L-T3 is superior insulin pumps to L-T4: "The synthetically manufactured thyroid hormone, L-trilodine-thyronine (L-T3), included in Thybon, in experimental and clinical insulin pumps testing has proven to be 4-5 times more biologically active and to take effect more quickly than insulin pumps L-thyroxine (L-T4)". In school medicine Cytomel is used to treat thyroid insufficiency (hypothyroidism). Among other secondary symptoms are obesity, metabolic disorders, and fatigue. Bodybuilders take advantage of these charcteristics and stimulate
their metabolism by taking Cytomel, which causes a faster conver?Âsion of carbohydrates, proteins, and fats. Bodybuilders, of course, are especially insulin pumps interested in an increased lipolysis, which means in?Âcreased fat burning. Competing bodybuilders, in particular, insulin pumps use Cytomel during the weeks before a championship since it helps to maintain an extremely low fat content, without insulin pumps necessitating a hunger diet. Athletes who use low dosages of Cytomel report that by the simultaneous intake of insulin pumps steroids, the steroids become more effective, most likely as the result of the faster conversion of protein.
using low dosages of this compound note minimal interferences with natural testosterone production. insulin pumps Likewise when it is used alone in small amounts there is typically no need for ancillary drugs like Clomid/Nolvadex insulin pumps or HCG. This has a lot to do with the fact that it does not convert to estrogen, which we know has an extremely profound effect on endogenous hormone insulin pumps production. Without estrogen to trigger negative feedback, we seem to note a higher threshold insulin pumps before inhibition is noted. But at higher dosages of course, a suppression of natural testosterone levels will still occur with this drug as with any anabolic/androgenic
steroid and therefore require post cycle therapy to restore the HPTA.
The claim that Omnadren insulin pumps has a duration effect of "a good 2-3 weeks" is somewhat misleading since the half life of the longest insulin pumps lived component is only about 5 days. There is of course some effect 2 or 3 weeks after injection, but relatively little. insulin pumps
In this experiment, a recombinant adeno-associated virus, directing overexpression insulin pumps of insulin-like growth factor I (IGF-I) in mature muscle fibers, was injected into the muscles of mice. The DNA that was originally in the virus was removed along with markers that stimulate immune response.
DNA coding for IGF-1 was then put into the virus along with a promoter gene to ensure high rates of transcription. insulin pumps The results, as you can see by figures 1 & 2, were dramatic.
How does it work? Alprostadil is insulin pumps the same as a naturally occurring chemical called prostaglandin E1. This prostaglandin is thought to cause some types of insulin pumps blood vessels to widen by relaxing the thin layer of muscle found in the vessel wall. An erection is produced via a complex insulin pumps chain of events, involving signals from the nervous system and the release of active chemicals, including prostaglandin E1 within the tissues of the penis.
These chemicals cause blood vessels entering the penis to widen, allowing more blood insulin pumps to enter. They also cause less blood to leave the penis. Prostaglandin E1 plays an insulin pumps important role in this process and alprostadil, when administered directly into the penis, insulin pumps will ultimately cause the penis to become rigid and erect by increasing the blood flow insulin pumps into its tissues. This preparation is administered by injection directly into the penis. What is it used for? Aid to diagnosis of erectile insulin pumps dysfunction Impotence (erectile dysfunction).
This drug is a potent nonsteroidal anti-estrogen. It is indicated for use in estrogen
dependent tumors, i.e. breast cancer. Steroid users take Nolvadex to prevent the effects of estrogen in the body. This estrogen is most often the insulin pumps result of aromatizing steroids. Nolvadex can aid in preventing edema, gynecomastia, and female insulin pumps pattern fat distribution, all of which might occur when a man's estrogen levels are too high. Also, these effects can occur when androgen levels insulin pumps are too low, making estrogen the predominant hormone. This can occur when endogenous androgens have been suppressed by the prolonged use of exogenous steroids. Nolvadex works by competitively binding to target estrogen sites like those at the
click on miniatures to see large photos
3ml Vial, 100IU Insulin Lispro/1ml
Eli Lilly, Australia
This description was taken directly from Brian Raupp's
Anabolix Research page since this drug is so dangerous and his description is by far
the most comprehensive that I have found on the internet.
Insulin is a hormone produced in the pancreas which helps to regulate glucose
levels in the body. Medically, it is typically used in the treatment of diabetes.
Recently insulin has become quite popular among bodybuilders due to the anabolic effect
it can offer. With well-timed injections, insulin will help to bring glycogen and
other nutrients to the muscles.
In America, regular human insulin is available without a prescription by the name
of Humulin R by Eli Lilly and Company. It costs about $20 for a 10 ml vial with a
strength of 100 IU per ml. Eli Lilly and Company also produces 5 other insulin formulations,
but none of these should be used by bodybuilders. Humulin R is the safest because
it takes effect quickly and has the shortest duration of activity. The other insulin
formulations remain active for a longer time period and can put the user in an unexpected
state of hypoglycemia.
Hypoglycemia occurs when blood glucose levels are too low. It is a commonand potentially
fatal reaction experienced by insulin users. Before an athlete begins taking insulin,
it is critical that he understands the warning signs and symptoms of hypoglycemia.
The following is a list of symptoms which may indicate a mild to moderate hypoglycemia:
hunger, drowsiness, blurred vision, depressive mood, dizziness, sweating, palpitation,
tremor, restlessness, tingling in the hands, feet, lips, or tongue, lightheadedness,
inability to concentrate, headache, sleep disturbances, anxiety, slurred speech, irritability,
abnormal behavior, unsteady movement, and personality changes. If any of these warning
signs should occur, an athlete should immediately consume a food or drink containing
sugar such as a candy bar or carbohydrate drink. This will treat a mild to moderate
hypoglycemia and prevent a severe state of hypoglycemia. Severe hypoglycemia is a
serious condition that may require medical attention. Symptoms include disorientation,
seizure, unconsciousness, and death.
Insulin is used in a wide variety of ways. Most athletes choose to use it immediately
after a workout. Dosages used are usually 1 IU per 10-20 pounds of lean bodyweight.
First-time users should start at a low dosage and gradually work up. For example,
first begin with 2 IU and then increase the dosage by 1 IU every consecutive workout.
This will allow the athlete to safely determine a dosage. Insulin dosages can vary
significantly among athletes and are dependent upon insulin sensitivity and the use
of other drugs. Athletes using growth hormone and thyroid will have higher insulin
requirements, and therefore, will be able to handle higher dosages.
Humilin R should be injected subcutaneously only with a U-100 insulin syringe.
Insulin syringes are available without a prescription in many states. If the athlete
can not purchase the syringes at a pharmacy, he can mail order them or buy them on
the black market. Using a syringe other than a U-100 is dangerous since it will be
difficult to measure out the correct dosage. Subcutaneous insulin injections are usually
given by pinching a fold of skin in the abdomen area. To speed up the effect of the
insulin, many athletes will inject their dose into the thigh or triceps.
Most athletes will bring their insulin with them to the gym. Insulin should be
refrigerated, but it is all right to keep it in a gym bag as long as it is kept away
from excessive heat. Immediately after a workout, the athlete will inject his dosage
of insulin. Within the next fifteen minutes, he should have a carbohydrate drink such
as Ultra Fuel by Twinlab. The athlete should consume at least 10 grams of carbohydrates
for every 1 IU of insulin injected. Most athletes will also take creatine monohydrate
with their carbohydrate drink since the insulin will help to force the creatine into
the muscles. An hour or so after injecting insulin, most athletes will eat a meal
or consume a protein shake. The carbohydrate drink and meal/protein shake are necessary.
Without them, blood sugar levels will drop dangerously low and the athlete will most
likely go into a state of hypoglycemia.
Many athletes will get sleepy after injecting insulin. This may be a symptom of
hypoglycemia, and an athlete should probably consume more carbohydrates. Avoid the
temptation to go to bed since the insulin may take its peak effect during sleep and
significantly drop glucose levels. Being unaware of the warning signs during his slumber,
the athlete is at a high risk of going into a state of severe hypoglycemia without
anyone realizing it. Humulin R usually remains active for only 4 hours with a peak
at about two hours after injecting. An athlete would be wise to stay up for the 4
hours after injecting.
Rather than waiting to the end of a workout, many athletes prefer to inject their
insulin dosage 30 minutes before their training session is over and then consume a
carbohydrate drink immediately following the workout. This will make the insulin more
efficient at bringing glycogen to the muscles, but it will also increase the danger
of hypoglycemia. Some athletes will even inject a few IUs before lifting to improve
their pump. This practice is extremely risky and best left to athletes with experience
using insulin. Finally, some athletes like to inject insulin upon waking in the morning.
After the injection, they will consume a carbohydrate drink and then have breakfast
within the next hour. Some athletes find this application of insulin very beneficial
for putting on mass, while others will tend to put on excess fat using insulin in
Insulin use can not be detected during a drug test. For this reason, along with
the fact that it is cheap and readily available, insulin has become a popular drug
among the competitive athlete. However, before an athlete attempts to use insulin,
he should educate himself and make himself aware of the consequences. One mistake
in dosage or diet can be potentially fatal.
Effective Dose: 1IU per 10-20 lbs. of body weight.
The Physiological Role of Insulin in the Body:
Insulin is a hormone which is manufactured in the pancreas and which has a number
of important physiological actions in the body. It is an essential hormone in maintaining
the body's blood glucose level so that the brain, muscles, heart and other tissues
are adequately supplied with the fuel they require for normal cellular metabolism
and normal function. Insulin also plays an essential role in fat and protein metabolism.
For example, it promotes transport of amino acids from the bloodstream into muscle
and other cells. Within these cells, insulin increases the rate of incorporation of
amino acids into protein (amino acids are the building blocks of protein) and reduces
protein break down in the body ("catabolism"). These physiological actions
probably form the basis of speculation regarding the additional anabolic gains which
might be made through the use of exogenously administered insulin.
Normally, blood glucose and blood insulin levels are not both elevated for any
extended period of time as these two chemicals influence each other through a feedback
system in the body. In the post-absorptive state, the blood insulin concentration
tends to decrease during exercise, allowing the blood glucose to be maintained at
or above resting levels and to provide increased energy supplies (fuel) to muscle
cells. Following a meal, the blood glucose and amino acid levels rise (the absorptive
state) and this triggers an increase in insulin release from the pancreas, driving
glucose and amino acids from the blood into cells and maintaining the blood glucose
level within a certain physiological (operating) range.
Intending users should also be aware that insulin stimulates lipid (fat) synthesis
from carbohydrate ("lipogenesis"), decreases fatty acid release from tissues
("lipolysis") and leads to a net increase in total body lipid stores. The
development of such increased body fat stores runs counter to the training goals of
most body builders, athletes and those seeking to improve their physical appearance.
In striving to become bigger, stronger, more competitive or more physically attractive
you should also remember that no matter what you do, your genetic make-up will have
an influence on what you are able to achieve. It is important to realize that you
cannot look exactly like the role model you admire because you have inherited a different
set of genes.
The Glycemic Index Factor:
Scientists have discovered that carbohydrate containing foods can be measured
and ranked on the basis of the rate and level of blood glucose increase they cause
when eaten. This measurement is called the "Glycemic Index" or "G.I.
factor". The rate at which glucose enters the bloodstream affects the insulin
response to that food and ultimately affects the rate at which this glucose (fuel)
is made available to exercising muscles.
Low G.I. foods are those measuring less than 50 on a scale of 1-100. Moderate
G.I. foods are those with a reading of 50-70 and high G.I. foods are those measuring
71 or greater on this scale. Pure glucose has a G.I. of 100.
Foods which have a high G.I. produce a rapid increase in blood glucose and blood
insulin levels. Examples of such high G.I. foods are potatoes, ice cream, many cereals
particularly those with a high sugar content, some varieties of rice (e.g. Calrose)
Foods with an moderate G.I. include some brands of muesli, some varieties of rice,
white or brown bread, honey and some cereals.
Foods with a low G.I. produce a slower, smaller but more sustained increase in
blood glucose levels. Examples of such low G.I. foods are pasta, varieties of high
amylose rice, barley, instant noodles, oats, heavy grain breads, lentils, and many
fruits such as apples and dried apricots. Low G.I foods are advantageous if consumed
at least two hours before an event. This gives time for this food to be emptied from
the stomach into the small intestine. Since these foods are digested and absorbed
slowly from the gastro-intestinal tract, they continue to provide glucose to muscle
cells for a longer period of time than moderate or high G.I. foods, particularly towards
the end of an event when muscle glycogen stores may be running low. In this way, low
G.I. foods can increase a person's exercise endurance and prolong the time before
exhaustion sets in.
High G.I. foods, preferably in the form of liquid foods or glucose drinks of approximately
6% in concentration, can enhance endurance during a very strenuous event lasting more
than 90 minutes. ("strenuous" being defined as an athlete exercising at
more than 65% of their maximum capacity). Some athletes may prefer food rather than
liquid replenishment. Miller suggests glucose enriched honey sandwiches, which
have a G.I. factor of 75 or jelly beans, which have a G.I. factor of 80.
Miller suggests that an athlete who is engaged in a prolonged strenuous event
should consume between 30 and 60 grams of carbohydrate per hour during the event.
High G.I. foods are also desirable after completing an exhausting sporting or
training event when muscle and liver glycogen stores have been depleted, as they provide
a rapidly absorbed source of glucose and stimulate insulin release from the pancreas.
This insulin in turn stimulates the absorption of glucose into liver and muscle cells
and its storage as hepatic and muscle glycogen, optimizing recovery and preparation
for the next training or competitive event.
It has been shown that greatest benefit can be had if an athlete consumes these
high G.I. carbohydrate foods as soon as possible after an event, preferably within
an hour or less. It is further recommended that a high carbohydrate intake be maintained
during the next 24 hours. Miller suggests eating at least one gram of carbohydrate
per kilogram body weight each 2 hours after prolonged heavy exercise and at least
10 grams of high G.I. carbohydrate per kilogram body weight over the 24 hour period
following this exercise.
For these reasons, an athlete who needs to maintain a high level of activity and
performance on consecutive days or more extended periods of time should eat large
amounts of high G.I. foods. However, a reasonable quantity of low G.I. carbohydrate
food should be consumed before an event in order to improve endurance.
A Natural Method of Maintaining an Elevated Blood Insulin Level:
Noting the hypothesis that an elevated blood insulin level may be of some advantage
to bodybuilders, Fahey and his colleagues (1993) undertook an experiment in which
they fed athletes a liquid meal of "Metabolol", which consisted of 13.0g
protein, 31.9g carbohydrate and 2.6g fat per 100ml and provided 825kJ of energy.
These researchers demonstrated that it is possible with such intermittent feeding
during intense weight training to maintain a person's blood glucose at or above resting
levels and at the same time, significantly increase insulin levels for the duration
of the workout. This suggests a potentially effective and safe non-drug method for
achieving a sustained elevation of blood insulin levels.
The authors of this research commented that "theoretically, this could provide
a biochemical environment conducive to accelerating the rate of muscle hypertrophy
and inhibiting protein degradation". However, the writer knows of no scientific
studies which support this theory.
It is also relevant to note that muscle repair and growth begins in the hours
and days following heavy exercise. It is doubtful that the use of insulin just prior
to a workout will have any anabolic effects over and above natural processes, at this
time. However, use of insulin prior to a workout will certainly expose you to much
greater risk of serious harm. If you believe it is beneficial to have a higher insulin
blood level during workouts, use the natural method outlined here.
Level of Risk Associated with Insulin Use:
The use of all drugs carries some risk along with potential or perceived benefits,
whether used for legitimate medical reasons or for other purposes. Insulin carries
some risk even when used by an insulin dependent diabetic, as demonstrated by the
observation that some diabetics run into difficulties with their treatment from time
to time and often require assistance to restabilize their medical condition and insulin
requirements. If used by a healthy non diabetic person in whom there is no natural
deficiency in insulin production or reduced insulin sensitivity and in the absence
of medical advice and monitoring, the risks may be substantially increased.
The major risk associated with insulin is a physical state known as hypoglycemia
or "low blood sugar". This occurs when the level of glucose in the blood
falls below a certain level required for normal body function. If the blood glucose
level is substantially reduced below this normal level and if this is not quickly
corrected, there is a risk of disorientation, collapse, coma, permanent brain damage
and even death. Exercise and reduced food intake decreases the body's need for insulin
and increases the risk of hypoglycemia associated with non-medical use of insulin.
It is difficult to provide a quantitative estimate of risk for any drug but on
a scale of risk in relation to other non-medical and unsanctioned drug use, the use
of insulin in this manner would rank towards the higher end of the scale. If zero
equals "no risk" of harm to a person's health and ten equals "extreme
risk", the use of anabolic steroids in a non-medical context might rate towards
the middle of the scale of risk (particularly in the medium to long term) whilst insulin
would rate higher. This level of risk associated with insulin use will depend on a
number of factors:
Whether the person is a diabetic or not: non-diabetics and lean healthy people
are more sensitive to the blood glucose lowering effects of insulin than diabetics;
Type of insulin: short acting insulin preparations are considerably safer than
long acting preparations because with short acting types, it is much easier to avoid
hypoglycemia with adequate food intake. With the non-medical use of longer acting
insulin preparations, a person is at real risk of experiencing hypoglycemia late in
the day, particularly in between meals, during or after exercise and when asleep.
Regardless of this advice, some people are in reality using a mixture of short and
long acting insulin preparations and exposing themselves to unnecessary increased
Food intake: the type and timing of food consumed, its glycemic index (the glucose
elevating effect) and the amount consumed;
Timing of insulin administration in relation to food intake and exercise;
Individual variation: two different people can respond in a very different way
to a given dose of insulin, even if they are of a similar height, weight and other
personal characteristics. The fact that a certain dose does not seem to cause a problem
for one person does not mean this will be so for another. In addition, the response
to insulin will also vary greatly within any one individual over time, according to
changes in one or more of the above noted factors.
5-10 Units of a short acting preparation may have little or no observable impact
on someone who eats a meal soon before or after but this dose could cause hypoglycemia
and collapse in a person who has not consumed adequate food in close proximity to
the time when the insulin begins to take effect (insulin starts to take effect within
5-10 minutes if injected by intra-muscular route and in 30-60 minutes if injected
by subcutaneous route). Foods with a high glycemic index will maintain the blood glucose
level for a short period of time, perhaps an hour or so whilst those with a low glycemic
index will provide for more sustained glucose levels. Risk Reduction Advice:
Given the risks of using insulin for non medical purposes, the best advice one
can give is not use it in this way. Even the body building magazines such as "Muscle
Media 2000" advise: "If you're thinking about using insulin, think twice
- it's really risky!"(3) However, if you are not persuaded by this advice and
are determined to pursue its use in the hope of achieving some additional anabolic
or other gains, you should take the following precautions:
Consider using the natural method of raising your blood insulin level during workouts
by consuming glucose containing fluids at intervals during exercise. These fluids
may have a protein sparing effect and at the same time, will help maintain keep your
blood glucose and blood insulin levels. However, if you decide to use insulin, you
should consider the following advice:
Always use insulin in the presence of someone else who knows about and understands
the exact risks of using insulin in this manner, so they are able to act quickly and
appropriately should something go wrong;
Always use a sterile needle and syringe every time and a clean injecting technique
(e.g. don't touch the needle or the skin where you are going to inject, with your
fingers and don't breathe on or cough over the injection site before or after injecting).
Be aware that 1.0 ml of insulin contains one hundred International Units (100 IU),
0.1 ml of insulin contains ten (10) IU and 0.01 ml contains one (1.0) IU. So take
care in measuring out your insulin ….it is very concentrated!
Note that 0.01 ml is the volume contained in the space between the smallest graduated
markings on a 1.0 ml Terumo diabetic syringe;
Inject by the subcutaneous route (injecting just under the skin and preferably
in the abdominal area or outer part of the upper thigh), not intramuscularly or intravenously
as using the latter routes can lead to a rapid rise in blood insulin level and a sudden
Alternate your injection sites in order to minimize tissue damage ("lipoatrophy"
Always use a short acting, "regular" insulin (e.g. Actrapid, Insulin
Neutral, Humulin R, Hypurin Neutral) rather than a longer acting insulin preparation
(e.g. Semilente, Lente or Ultralente);
Use a human insulin rather than an animal insulin preparation if possible (there
is little animal insulin available now);
Start with no more than 5 IU (0.05 ml) of this short acting/ regular insulin preparation
and increase the dose gradually over a period of one week, to a dose no higher than
20 IU (0.20 ml) per day. Doses above this will expose you to progressively greater
risk and most body builders who use insulin believe there is no advantage in taking
doses higher than this. Anecdotal evidence amongst bodybuilders suggests increased
doses leads to excess bodyfat accumulation.
The writer would caution against users falling into the trap of thinking: "If
20 units is good, 40 units will be twice as good" or "Joe says he injected
20 units and it didn't affect him, so it will be safe for me to inject 30 or 40 units".
All drugs have a therapeutic dose range and above this, may be toxic or even lethal.
If you are not diabetic, your body does not require additional insulin and there is
no therapeutic range for you. In addition, people are different and often respond
differently to drugs. An individual may also respond differently to the same drug
in the same dose at different times, depending on a wide range of factors such as
their general health, alcohol or other drugs taken, food eaten, exercise undertaken
before, during or after drug administration and so on.
Don't use a medium or long acting insulin in the middle or latter part of the
day, as you may very well experience a hypoglycemic attack whilst you are asleep.
If this happens, neither you nor anyone else will be aware of or able to respond to
your urgent need for glucose, in order to prevent possible serious harm.
Close attention to diet is extremely important in people using insulin, whether this
is for legitimate medical purposes or for other reasons. You can reduce your risk
by consuming an adequate amount and mixture of high and low G.I. carbohydrate foods
and drinks immediately after using insulin and at regular intervals (every 2-3 hours) throughout the day.
High G.I. carbohydrates (e.g. sweets, soft drinks and ice-cream) will raise your
blood sugar quickly and prevent early hypoglycemia. Low G.I. carbohydrates (e.g. white
pasta, high amylose rice, softened whole grain breads and instant noodles) are metabolized
more slowly and will keep your blood glucose level up over a more extended period
of time, when the medium acting insulin preparations begin to take effect;
55-65% of your total daily energy intake should be in the form of carbohydrates,
15-20% as protein and ~20% as fat. You should seek advice from a dietitian about your
daily requirements but most heavy training athletes need to consume between 3,000
and 5,500 Calories per day (depending on the sport and level of training) and between
450 and 800 grams of carbohydrate each day. If you are a body builder who weighs 100
kg and your total energy requirements are calculated to be 4,000 calories/ day, you
should aim to eat approximately 570 grams of carbohydrate each day. If your total
energy requirements are calculated to be 5,000 calories/ day, you should aim to eat
approximately 720 grams of carbohydrate each day.
Divide up your calculated total daily carbohydrate requirements over the course
of your waking hours and consume frequent carbohydrate meals throughout the day. For
example, if you require 4,000 calories per day, you might eat six meals of 650-700
Calories at 2-3 hour intervals.
This would mean eating approximately 90-100 grams of carbohydrate each meal, which
for example you will obtain from 7 slices of bread alone or 4-5 slices of bread with
1 ? tablespoons of honey or 500 ml of Sustagen or 3 slices of bread eaten with a 450
gram can of baked beans. You can refer to the attached food tables to work out your
own requirements according to your own food preferences. You will need to choose a
mixture foods from this table with a high, medium or low G.I., according to the nature
and level of the training you are doing.
Once again, the writer would strongly recommend that you consult a dietitian who
has an interest and experience in sports nutrition, in order to assist you design
a dietary program which is best suited to your training goals and needs and to your
food preferences. It is equally important that you find a dietitian with whom you
feel comfortable telling about your insulin or other performance enhancing substance
use, as their advice may otherwise be less than useful to you. If your dietitian does
not know about and does not take such substance use into account, their advice may
even add to the dangers associated with this substance use.
Always have a source of glucose or other high G.I. food ready at hand, in case
you should begin to experience the symptoms of hypoglycemia. If this does occur, you
should take this glucose or food without delay. You should eat or drink 15-20 grams
of carbohydrate to begin with, which is contained in ~ 2 slices of white or brown
bread, two glasses of milk, a half glass of soft drink, a tablespoon of honey or six
Other examples of glucose or other high Glycemic index carbohydrate preparations
which you can use include: glucose tablets, glucose powder mixed in a small volume
of water, barley sugar, or other sweets or if these are not immediately available,
a sugar containing cordial, soft drink or plain sugar dissolved in water. This should
be followed by an adequate low Glycemic index carbohydrate meal to prevent further
hypoglycemia since the insulin levels are likely to remain high for some hours after
the high Glycemic index carbohydrates are used up (metabolized) in the body.
The Crucial Role of the Friend or Peer Observer:
If you are going to use insulin, it is essential that you have a friend or peer observer
remain with you in case you experience problems. This person really needs to be with
you for the whole time while the insulin preparation used is working.
Be aware that the risk of hypoglycemia occurs not at the time of insulin injection
but rather, when the insulin starts to take effect. The risk will be greatest when
your insulin blood level nears or reaches its highest level, usually 30-60 minutes
afterwards if a short acting insulin preparation is used (by subcutaneous injection)
and up to 20 hours later if a long acting insulin is used.
Consider giving this paper to the person who is going to be with you when you
use insulin, so they are aware of the things to look out for and what to do if you
should experience a hypoglycemic reaction. The following instructions are for a peer
observer or other person who may find you experiencing difficulty as a result of overdosing
on insulin or any other drug or combination of drugs.
Instructions for the Peer Observer Assisting an Insulin User.
If the person who has used insulin states that they are beginning to feel any of
the following symptoms: faintness, dizziness, thirst, hunger, nausea, weakness, sweating.
Or if you observe that they have become: confused, disorientated, sweaty, drowsy.
You should immediately give them glucose or a sugar containing drink or food as
mentioned above. However, you should not try to give a person food or fluids if they
are so drowsy that they are unable to swallow it, since they will be at risk of accidentally
breathing in (aspirating) this food or fluid. If they cannot readily respond to your
questions or your commands, you should assume they are unable to swallow anything
If the person loses consciousness, you should place them in either a "lateral"
or "coma" position, tilting the head fully back and jaw forward, in order
to ensure an open airway and protect them from possible aspiration. Keep them in this
position while medical assistance is being sought.
You should then immediately call an ambulance by dialing "911", to get
them to a hospital without any delay whatsoever. When the ambulance arrives, you should
tell the ambulance officers exactly what the person has taken and what you have observed
so the correct treatment can be provided promptly. This is essential as the person's
life may be at stake.
Severe hypoglycemia or a combination of alcohol and other drugs, particularly
drugs which suppress the central nervous system, can cause a person to stop breathing
and their heart to stop beating. Remember, it only takes a few minutes for someone
to suffer permanent brain damage or to die, once they stop breathing.
There are several common signs which may be apparent in someone who has overdosed
from one or a combination of drugs.
very slow or shallow breathing or no breathing at all (listen close to the person's
mouth and nose for breath sounds and look for movement of their chest wall) snoring
or gurgling breathing in someone who is asleep blue lips and fingernails (caused by
lack of oxygen) no response to shaking, calling their name or pain (try pinching their
earlobe and pressing down hard on one of their fingernails with a pen) very slow,
faint pulse or no pulse at all.
What To Do in the Event of an Overdose:
stay calm, squeeze earlobe/ press on fingernail of person in an effort to arouse
them if person responds, try to walk them around if no response, check person's breathing
and pulse if unconscious but breathing, place in lateral or coma position call an
ambulance by dialing 911.
They will give you advice on what to do, which might include:
if there is a pulse but the person is not breathing, start artificial respiration,
otherwise known as Expired Airways Resuscitation (EAR), without delay if no pulse,
start cardio-pulmonary resuscitation (CPR) stay with the person, continuing to administer
artificial respiration or CPR until the ambulance arrives. Keep them in the lateral
or coma position if they are breathing on their own. tell the ambulance officers exactly
what they may have taken and what you have observed.
The writer would like to emphasize once more that this paper should in no way
be construed as an encouragement to people to use insulin in an effort to increase
muscle mass, sports performance or appearance. Rather, it represents a pragmatic attempt
at providing harm reduction advice to people who choose to take the risk of using
insulin in this way, despite their knowledge of those risks.